![](/images/graphics-bg.png)
Influence of olive and rosemary leaves extracts on chemically induced liver cirrhosis in male rats
Joint Authors
al-Attar, Atif M.
Shawish, Nisrin A.
Source
Saudi Journal of Biological Sciences
Issue
Vol. 22, Issue 2 (30 Jun. 2015), pp.157-163, 7 p.
Publisher
Publication Date
2015-06-30
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
Abstract EN
The current study was undertaken to evaluate the protective activity of olive and rosemary leaves extracts on experimental liver cirrhosis induced by thioacetamide (TAA) in Wistar male rats.
Highly significant decline in the values of body weight gain and highly statistically increase of liver / body weight ratio were noted in rats treated with TAA.
Furthermore, the levels of serum alanine aminotransferase, aspartate aminotransferase, gamma glutamyl transferase, alkaline phosphatase and total bilirubin were statistically increased.
Additionally, light microscopic examination of liver sections from rats treated with TAA showed a marked increase in the extracellular matrix collagen content and bridging fibrosis was prominent.
There were bundles of collagen surrounding the lobules that resulted in large fibrous septa and distorted tissue architecture.
Interestingly, the findings of this experimental study indicated that the extracts of olive and rosemary leaves and their combination possess hepatoprotective properties against TAA-induced hepatic cirrhosis by inhibiting the physiological and histopathological alterations.
Moreover, these results suggest that the hepatoprotective effects of these extracts may be attributed to their antioxidant activities.
American Psychological Association (APA)
al-Attar, Atif M.& Shawish, Nisrin A.. 2015. Influence of olive and rosemary leaves extracts on chemically induced liver cirrhosis in male rats. Saudi Journal of Biological Sciences،Vol. 22, no. 2, pp.157-163.
https://search.emarefa.net/detail/BIM-527399
Modern Language Association (MLA)
al-Attar, Atif M.& Shawish, Nisrin A.. Influence of olive and rosemary leaves extracts on chemically induced liver cirrhosis in male rats. Saudi Journal of Biological Sciences Vol. 22, no. 2 (2015), pp.157-163.
https://search.emarefa.net/detail/BIM-527399
American Medical Association (AMA)
al-Attar, Atif M.& Shawish, Nisrin A.. Influence of olive and rosemary leaves extracts on chemically induced liver cirrhosis in male rats. Saudi Journal of Biological Sciences. 2015. Vol. 22, no. 2, pp.157-163.
https://search.emarefa.net/detail/BIM-527399
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 162-163
Record ID
BIM-527399