Comparison of renal function following donor nephrectomy versus radical nephrectomy for renal tumor
Joint Authors
Abd Al-Al, M. A.
Etafy, Muhammad
Salih, Fatimah
Gawish, Mahir
Mursi, Jamal
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 26, Issue 2 (30 Apr. 2015), pp.238-242, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2015-04-30
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
- Patients
- Kidneys
- Diseases
- Penal functions
- Medical examinations
- Cancer
- Organ transplantation
- Excision(Surgery)
- Complications(Medicine)
- Diagnosis
Abstract EN
In this study, we compared renal function in patients after donor nephrectomy (DN) and radical nephrectomy (RN).
We retrospectively reviewed 68 patients (mean follow-up 15 months), including 30 patients who had undergone DN and 38 patients who had undergone RN.
The study was performed between April 2006 and July 2010 at a single institute.
Patients were matched for age and co-morbidities (hypertension and diabetes mellitus).
We calculated the estimated glomerular filtration rate (eGFR) using the Modification of Diet in Renal Disease study group equation.
Parameters studied included GFR (≥ 60 to < 60 mL / min / 1.73 m2), serum creatinine (> 2.0 mg / dL), metabolic acidosis (serum bicarbonate < 22 mmol / L) and proteinuria (> 30 mg).
There were no significant demographic differences between the two study groups.
After a mean follow-up of 15 months, low eGFR (< 60 mL / min / 1.73 m2) was seen in 28 % and 6.7 % of patients in the RN and DN groups, respectively (P = 0.03).
Similarly, proteinuria was seen in 21 % vs 0 %, P = 0.007, and de novo elevated creatinine was seen in 13 % vs 0 %, respectively P = 0.04 ; thus the changes were greater in the RN group.
Our study shows that undergoing RN had a significantly greater risk of developing renal insufficiency and proteinuria compared with ageand co-morbidity-matched patients undergoing DN.
We concluded that patients undergoing RN show a significantly greater risk of developing renal insufficiency and proteinuria compared with the patients undergoing DN.
American Psychological Association (APA)
Etafy, Muhammad& Salih, Fatimah& Abd Al-Al, M. A.& Gawish, Mahir& Mursi, Jamal. 2015. Comparison of renal function following donor nephrectomy versus radical nephrectomy for renal tumor. Saudi Journal of Kidney Diseases and Transplantation،Vol. 26, no. 2, pp.238-242.
https://search.emarefa.net/detail/BIM-532371
Modern Language Association (MLA)
Etafy, Muhammad…[et al.]. Comparison of renal function following donor nephrectomy versus radical nephrectomy for renal tumor. Saudi Journal of Kidney Diseases and Transplantation Vol. 26, no. 2 (2015), pp.238-242.
https://search.emarefa.net/detail/BIM-532371
American Medical Association (AMA)
Etafy, Muhammad& Salih, Fatimah& Abd Al-Al, M. A.& Gawish, Mahir& Mursi, Jamal. Comparison of renal function following donor nephrectomy versus radical nephrectomy for renal tumor. Saudi Journal of Kidney Diseases and Transplantation. 2015. Vol. 26, no. 2, pp.238-242.
https://search.emarefa.net/detail/BIM-532371
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 241-242
Record ID
BIM-532371