Nailfold and labial in vivo capillary microscopy in systemic sclerosis
Other Title(s)
الفحص المجهري الحيوي للشعيرات الدموية بمنبت الأظافر و الغشاء المخاطي للشفاه في مرضى التصلب (الجلدي) الشمعي
Joint Authors
Kamil, Nadiyah Salah
Tamarah, Fathi
al-Hifnawi, Hanan al-Sibai
al-Tayyib, Muhammad Nasir
Source
Egyptian Rheumatology and Rehabilitation
Issue
Vol. 20, Issue 2 (30 Apr. 1993), pp.97-110, 14 p.
Publisher
The Egyptian Society for Rheumatology and Rehabilitation
Publication Date
1993-04-30
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Systemic sclerosis (SSc) is characterized by a wide spread vascular disease.
This study was designed to assess the vascular damage in patients with SSc by in vivo capillary microscopy of the conventional site; the nailfold, as well as a second window; the labial mucosa.
The study included 17 patients (all females) suffering from SSc as well as 5 healthy controls.
Nailfold and labial capillary microscopy was done to assess loop length, loop width (lumen included), loop density number/linear mm, enlarged capillaries, avascualar areas, hemorrhages, and the architectural arrangement of the capillary network.
Conventional nailfold capillary microscopy revealed shorter loop length, wider loop, and decreased number of capillaries/linear mm in SSc than normal control.
The SSc patients capillaries were markedly tortuous, with frequent megacapillaries, avascualar areas, and less frequently hemorrhages.
Labial capillary microscopy proved as valuable as conventional nailfold examination.
Labial capillaries were far easier to examine than nailfold capillaries due to the transparency of labial mucosa.
In SSc patients there was loss of the normal organized architectural pattern of the capillaries.
Hemorrhages were detected more frequently in labial mucosa than in nailfold, also enlarged capillaries, avascular areas, and very short capillaries were also noted.
However, measurements of capillary loop length and width were not as accurately recorded as those of the nailfold capillaries, but still were shorter and wider than healthy controls, respectively.
Nailfold capillary microscopy is a valuable means of assessment of microvasculature in vivo for patients with SSc.
It is noninvasive, informative, and reproducible.
Labial capillaroscopy can be used when the nailfold is damaged or pigmented.
Also, it is less affected by cold stress, chemical or mechanical factors.
Patients with SSc showed a typical scleroderma pattern of microvascular changes when compared to controls.
American Psychological Association (APA)
Tamarah, Fathi& al-Tayyib, Muhammad Nasir& Kamil, Nadiyah Salah& al-Hifnawi, Hanan al-Sibai. 1993. Nailfold and labial in vivo capillary microscopy in systemic sclerosis. Egyptian Rheumatology and Rehabilitation،Vol. 20, no. 2, pp.97-110.
https://search.emarefa.net/detail/BIM-535861
Modern Language Association (MLA)
Tamarah, Fathi…[et al.]. Nailfold and labial in vivo capillary microscopy in systemic sclerosis. Egyptian Rheumatology and Rehabilitation Vol. 20, no. 2 (Apr. 1993), pp.97-110.
https://search.emarefa.net/detail/BIM-535861
American Medical Association (AMA)
Tamarah, Fathi& al-Tayyib, Muhammad Nasir& Kamil, Nadiyah Salah& al-Hifnawi, Hanan al-Sibai. Nailfold and labial in vivo capillary microscopy in systemic sclerosis. Egyptian Rheumatology and Rehabilitation. 1993. Vol. 20, no. 2, pp.97-110.
https://search.emarefa.net/detail/BIM-535861
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 107-108
Record ID
BIM-535861