Clinical trial of immunotherapy with paternal mononuclear cells for unexplained recurrent miscarriage
Joint Authors
Source
Issue
Vol. 9, Issue 1 (30 Jun. 2000), pp.18-21, 4 p.
Publisher
Publication Date
2000-06-30
Country of Publication
Qatar
No. of Pages
4
Main Subjects
Topics
Abstract EN
The effect of immunotherapy with paternal leukocytes for the treatment of unexplained recurrent miscarriage is controversial.
To further investigate this we immunized S6 women with two or more previous miscarriages with approximately 0.5 × 109 paternal mononuclear cells.
Another 63 recurrent miscarries who conceived during the same period were used as controls.
There was no overall positive effect of paternal leukocyte transfusion but among women with three or-more miscarriages the success rate was significantly higher in the treatment group (p < 0.01) than the controls (83.9 % versus 51.7 %).
We found a significantly higher success rate (90 %) in the group immunized during pregnancy compared to (60 %) the group immunized before pregnancy (p < 0.05).
Conclusion : all immunization with paternal leukocytes showed a positive effect on the live birth rate in a subset of women with three or more miscarriages.
This treatment should not be offered to patients with a history of only two miscarriages and preferably it should be performed as early as possible during pregnancy.
American Psychological Association (APA)
Sad, Fawwaz A.& al-Hilali, A.. 2000. Clinical trial of immunotherapy with paternal mononuclear cells for unexplained recurrent miscarriage. Qatar Medical Journal،Vol. 9, no. 1, pp.18-21.
https://search.emarefa.net/detail/BIM-537458
Modern Language Association (MLA)
Sad, Fawwaz A.& al-Hilali, A.. Clinical trial of immunotherapy with paternal mononuclear cells for unexplained recurrent miscarriage. Qatar Medical Journal Vol. 9, no. 1 (Jun. 2000), pp.18-21.
https://search.emarefa.net/detail/BIM-537458
American Medical Association (AMA)
Sad, Fawwaz A.& al-Hilali, A.. Clinical trial of immunotherapy with paternal mononuclear cells for unexplained recurrent miscarriage. Qatar Medical Journal. 2000. Vol. 9, no. 1, pp.18-21.
https://search.emarefa.net/detail/BIM-537458
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 21
Record ID
BIM-537458