The effect of denervation on fracture healing : an experimental study on rabbits

Abstract EN

Many studies suggested a relation between denervation and fracture healing either in positive or negative effect.

This is a prospective experimental study on 20 rabbits carried out in the experimental animal’s research laboratory of Basrah University, Medical College from April 2014 to November 2014 according to ethical rules of institution.

They were housed under controlled conditions of temperature and lighting, same diet was given for all animals.

The rabbits was divided into two groups ; group A with sciatic denervation and fracture of the tibia while group B, with fracture tibia only.

The state of fracture healing was studied radiologically after 4 weeks and histopathologically at 6 weeks.

The results showed significant difference between the two groups, the denervated group had poor fracture healing compared with non denervated group.

In conclusion, denervation affects fracture healing negatively in rabbits.