The effect of inhaled corticosteroid on oral conditions among asthmatic children

Abstract EN

Background: Inhalation therapy has been employed as the mainstay of the treatment in chronic respiratory diseases such as asthma, Patients who taking asthma medication may be at risk of many health problems including oral health .The purpose of this study was to assess the local effect of ICS on oral tissue by measuring Candida albicans count colonies in saliva among12 years old asthmatic children who were collected from AL- Zahra Center Advisory for Allergy and Asthma, and compares them with non asthmatic children of the same age and gender.

Material and Methods: The total sample involved sixty children of 12 years old, thirty asthmatic children who received medium dose of ICS/day (200-400 microgram/day) for 2 years and 30 non-asthmatic children.

The unstimulated saliva was collected under standard condition and then analyzed for Candida albicans colony counts assessment.

Results: The mean rank of the colony counts were found to be higher among asthmatic than non- asthmatic children with statistically significant difference (P<0.05).

Concerning each gender, the results illustrated that the difference for boys was statistically non significant (P>0.05), while for girls the difference was statistically significant (P<0.05).

Concerning gender differences, data analysis showed that the mean rank of Colony counts were found to be higher among girls than boys in both groups with statistically non-significant difference (P>0.05) Conclusions: The findings of the present study showed that the asthmatic disease and ICS treatment play an important role in elevation of the candida prevalence in oral cavity.-