The effect of age and gender on fetuin-a and some biochemical parameters in blood sera of iraqi patients with t2dm : a comparative study

Abstract EN

The serum protein test includes measurement of the level of total protein(albumin, globulin).

Fetuin-A is a blood protein made in liver.

It can inhibit insulin receptor, enhance insulin sensitivity and make the individuals more likely to develop type 2 diabetes, then disorder in lipid profile (Total cholesterol(TC), low density lipoprotein cholesterol (LDL-c), high density lipoprotein cholesterol (HDL-c), Triglyceride(TG) and very low density lipoprotein cholesterol (VLDL-c) .

To evaluate Fetuin-A, total protein, albumin, globulin, HbAlc and lipid profile in 200 adult and elderly Iraqi patients with type 2 Diabetes Mellitus were taken and compare them with 200 subjects as a healthy control.

The laboratory analysis(for patients and control ) were performed to determine these parameters .The results show that FBG.

HbA1c, Lipid profile for (patients and control) (except HDL-c) were increase with age with a significant difference (p<0.01) between patients and control in each age and with no significant difference (p>0.05) between male and female.

Serum total protein, globulin, Fetuin-A, increase with age while albumin decrease with age(in patients and control).