New triterpene isovanniloyl and antibacterial activity of constituents from the roots of Paullinia pinnata Linn (Sapindaceae)‎

Abstract EN

In addition to lupeyl steryl ether (1) and 3-oxo-11a-hydroxyl-20 (29) lupen (2), a new lupeol-3-isovanniloyl ester (3) was isolated from Paullinia pinnata.

Using detailed 1D and 2D NMR spectra and comparison with the published data, the new compound was characterised as 3-O-isovanilloyl-3R,5R,8R,9R,10R,13R,14S,17S,18R,19R-lup-20(29)-en, for which the trivial name Paullinoyl was proposed.

Compound 3 demonstrated significant antibacterial activity on the tested strains (MIC 15.2–30.20 lg/ml).

The antibacterial activities obtained in this study confirmed the use of P.

pinnata in traditional medicine for treating bacterial infections.