Asymptomatic hypoglycemia after hemodialysis in non-diabetic patients with use of glucose-free dialysate solutions

Abstract EN

Hypoglycemia (HG) has been demonstrated during chronic hemodialysis (HD).

These events may become more frequent with the current use of glucose-free bicarbonate dialysis solution, the standard formula in most dialysis units in our hospitals.

The Aim of study is to evaluate the occurrence of HG in non-diabetic (NDM) end-stage renal failure patients during HD using dialytic solution without glucose.

In Merjan teaching hospital from January to September 2013.

A hospital-based cross-sectional study design has been carried out on fifty non-diabetic patients with chronic renal failure randomly selected from the dialysis unit of Merjan Teaching Hospital after their setting for HD session of the glucose- free bicarbonate solution.

Serum glucose has been measured at zero hour before dialysis session and 30 minutes after dialysis session.

The study duration was from … January …………to September 2013……..

Categorical variables were presented as frequencies and percentages.

Continuous variables were presented as means with their 95% confidence interval (CI) and standard deviation.

The Pearson's chi-square test (x2) was used to determine the associations between categorical variables.

Independent sample t-test was used to compare between two means.

A p-value of < 0.05 was considered as statistically significant.

Data were expressed No patient presented any clinical evidence of HG.40 patients(74.8%) of fifty patients express serum sugar levels changes before and after HD ,serum sugar levels after HD was <80mg/dl ,which is statistically significant P value <0.01.

Asymptomatic HG was frequent during HD when glucose-free dialysis solution was used.

Glucose added dialysis solution at 90 mg/dl significantly reduced the number and severity of HG episodes and although it caused higher mean glycaemia in DM patients during HD, its use seems advisable in all patients.