A simple two step synthesis of 6, 8-dihydroxy-3- (3',4'-dihydroxyphenylethenyl)‎ isocoumarin

Joint Authors

Said, Amir
Rama, Nasim Hasan

Source

The Arabian Journal for Science and Engineering

Issue

Vol. 21, Issue 3 (31 Jul. 1996), pp.403-406, 4 p.

Publisher

King Fahd University of Petroleum and Minerals

Publication Date

1996-07-31

Country of Publication

Saudi Arabia

No. of Pages

4

Main Subjects

Chemistry
Botany

Abstract EN

The title isocoumarin (3) isolated recently from the underground parts of the plant Achyls triphylla, by other authors, has been synthesized.

Direct reaction of 3,5-dimethoxyhomophthalic acid (4) with 3,4-dimethoxycinnamoyl chloride (5) afforded 6,8-dimethoxy-3-(3',4'-dimethoxyphenylethenyl)isocoumarin (6).

Complete demethylation of compound (6) was effected using boron tribromide in refluxing dichloromethane to give the title isocoumarin (3) in reasonable yield.

American Psychological Association (APA)

Said, Amir& Rama, Nasim Hasan. 1996. A simple two step synthesis of 6, 8-dihydroxy-3- (3',4'-dihydroxyphenylethenyl) isocoumarin. The Arabian Journal for Science and Engineering،Vol. 21, no. 3, pp.403-406.
https://search.emarefa.net/detail/BIM-559577

Modern Language Association (MLA)

Said, Amir& Rama, Nasim Hasan. A simple two step synthesis of 6, 8-dihydroxy-3- (3',4'-dihydroxyphenylethenyl) isocoumarin. The Arabian Journal for Science and Engineering Vol. 21, no. 3 (Jul. 1996), pp.403-406.
https://search.emarefa.net/detail/BIM-559577

American Medical Association (AMA)

Said, Amir& Rama, Nasim Hasan. A simple two step synthesis of 6, 8-dihydroxy-3- (3',4'-dihydroxyphenylethenyl) isocoumarin. The Arabian Journal for Science and Engineering. 1996. Vol. 21, no. 3, pp.403-406.
https://search.emarefa.net/detail/BIM-559577

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 406

Record ID

BIM-559577