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Treatment of premature ejaculation : a new combined approach
Joint Authors
Jamal, Raniya M.
Kurkar, Adil
Jad al-Mawla, Muhammad Mahmud Muhammad
Shalabi, Mahmud M.
Ghandur, Abir M.
al-Dirwi, Ahmad A.
al-Tahir, Ahmad M.
Abu al-Surur, Sharif M.
Safwat, Ahmad S.
Source
Egyptian Rheumatology and Rehabilitation
Issue
Vol. 42, Issue 1 (31 Mar. 2015), pp.39-44, 6 p.
Publisher
The Egyptian Society for Rheumatology and Rehabilitation
Publication Date
2015-03-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background Selective serotonin reuptake inhibitors (SSRIs) are utilized to treat premature ejaculation (PE).
However, their effect is moderate, with no universally adopted schedule.
A possible role for pelvic floor dysfunction in the pathogenesis of PE was reported previously.
Objective The aim of this study was to compare the efficacy of combined sertraline and pelvic floor rehabilitation with either line in patients with an unsatisfactory response to SSRIs.
Design, setting, and participants From June 2009 to December 2012, 74 PE patients with an unsatisfactory response to sertraline 50 mg were enrolled and subjected to pelvic floor rehabilitation as an alternative therapy, and then a combination of both was tested on the same group.
Outcome measurements and statistical analysis Relationships with outcome were analyzed using the Student t-test, Pearson’s correlation, and linear regression.
Results and limitations The baseline intravaginal ejaculatory latency time (IELT) was 20–110 s (mean ± SD = 56.35 ± 21.67).
With sertraline 50 mg therapy alone, IELT reached 90–180 s (mean ± SD = 121.69 ± 21.76, P = 0.0001).
Of them, 44 (59.46 %) patients failed to exceed an IELT of 120 s.
With pelvic floor rehabilitation alone, IELT reached 90–270 s (mean ± SD = 174.73 ± 45.79, P = 0.0001).
Of them, 13 (17.56 %) patients failed to exceed an IELT of 120 s.
Using a combination therapy of both, IELT reached 180–420 s (mean ± SD = 297.57 ± 59.19, P = 0.0001).
This response was significantly higher than the baseline IELT and that of either lines alone (P = 0.0001, for all tests).
Conclusion Pelvic floor rehabilitation is an important addition when treating PE, particularly in patients with pelvic floor dysfunction.
We recommend this combination in patients with an unsatisfactory response to SSRIs.
Patient summary Causes of PE differ considerably.
In this paper, we compared the outcomes of two single treatment lines together with a combination of both.
The combination therapy was more effective than either line alone.
American Psychological Association (APA)
Kurkar, Adil& Abu al-Surur, Sharif M.& Jamal, Raniya M.& al-Tahir, Ahmad M.& Safwat, Ahmad S.& al-Dirwi, Ahmad A.…[et al.]. 2015. Treatment of premature ejaculation : a new combined approach. Egyptian Rheumatology and Rehabilitation،Vol. 42, no. 1, pp.39-44.
https://search.emarefa.net/detail/BIM-560102
Modern Language Association (MLA)
al-Dirwi, Ahmad A.…[et al.]. Treatment of premature ejaculation : a new combined approach. Egyptian Rheumatology and Rehabilitation Vol. 42, no. 1 (2015), pp.39-44.
https://search.emarefa.net/detail/BIM-560102
American Medical Association (AMA)
Kurkar, Adil& Abu al-Surur, Sharif M.& Jamal, Raniya M.& al-Tahir, Ahmad M.& Safwat, Ahmad S.& al-Dirwi, Ahmad A.…[et al.]. Treatment of premature ejaculation : a new combined approach. Egyptian Rheumatology and Rehabilitation. 2015. Vol. 42, no. 1, pp.39-44.
https://search.emarefa.net/detail/BIM-560102
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 43-44
Record ID
BIM-560102