Inappropriate use of antibiotics in the treatment of pharyngo-tonsilitis in children in Khartoum, Sudan

Abstract EN

Pharyngo-tonsillitis represents a major public health problem all over the world.

Recent studies in Sudan have revealed alarming results reporting antibiotics over prescription in the management of acute tonsillitis.

Objectives : The aim of this study was to estimate the prevalence of Group A Beta hemolytic streptococci and document the appropriateness of using antibiotics in the treatment of acute tonsillo-pharyngitis in Jaafar Ibn Auf Pediatrics Hospital.

Materials and Methods : A cross sectional hospital based study was conducted in the period January to August 2012 in Jaafar Ibn Auf Hospital, the largest tertiary pediatrics hospital in Sudan.

The sample size was 100 including children aged 2-17 years and got antibiotics treatment for their current sore throat.

A pharyngeal swab was collected at presentation from tonsils and posterior pharynx.

Gram staining was done first, and then Group A Beta hemolytic streptococci were isolated and identified in the laboratory by their growth characteristics.

All children included in the study were assessed clinically and subjected to a structural questionnaire.

Data were analyzed by SPSS version 19.

Results : The estimated prevalence of Group A Beta hemolytic streptococci tonsillitis and/or pharyngitis was 22 %, nevertheless the proportion of antibiotic prescription was 100 %.

Conclusion : Most children were treated inappropriately regarding the need for using antibiotics, the type of antibiotics used and the duration of management.

As many studies suggested that increased using of antibiotics may be due to uncertainty of diagnosis, requesting scoring system or rapid diagnostic test can contribute to the reduction of the rate of antibiotics prescription.