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The effectiveness of systemic antibiotic therapy with and without ethanol-locked solution in the treatment of hemodialysis-related catheter infection
Joint Authors
Khosroshahi, Hamid Tayyibi
Mahdi Bur, Husayn
Parkhideh, Sahar
Basmenji, Said
Khalil Zadah, Muhammad Rida
Tozihi, Majid
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 26, Issue 3 (31 May. 2015), pp.477-481, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2015-05-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Bacterial overgrowth in the inner layer of the catheter as a biofilm is highly encountered in routine medical care, and it may occur in a few days after inserting a catheter as an access in hemodialysis (HD) patients.
Catheter-induced bacteremia is often due to the development of biofilms.
Locking catheters with antimicrobial agents is an effective way of reducing the risk of catheter-related infection.
In a controlled, randomized clinical trial, 64 chronic HD patients (32 men and 32 women with a mean age of 57.5 ± 15.6 years) were divided into case and control groups, with 32 patients in each group.
The case group received systemic antibiotic and a lock of catheters with 60 % ethanol and the control group received only systemic antibiotic.
The results were evaluated after three weeks of treatment.
The success rate of clearing infection in group A (29 patients) and group B (18 patients) was 90.6 % and 56.2 %, respectively (P = 0.002).
We conclude that the significant difference in the success rate of clearing catheter infection in HD patients is due to the use of 60 % ethanol-lock along with antibiotic therapy, and suggest this for routine use.
American Psychological Association (APA)
Khosroshahi, Hamid Tayyibi& Mahdi Bur, Husayn& Parkhideh, Sahar& Basmenji, Said& Khalil Zadah, Muhammad Rida& Tozihi, Majid. 2015. The effectiveness of systemic antibiotic therapy with and without ethanol-locked solution in the treatment of hemodialysis-related catheter infection. Saudi Journal of Kidney Diseases and Transplantation،Vol. 26, no. 3, pp.477-481.
https://search.emarefa.net/detail/BIM-567438
Modern Language Association (MLA)
Khosroshahi, Hamid Tayyibi…[et al.]. The effectiveness of systemic antibiotic therapy with and without ethanol-locked solution in the treatment of hemodialysis-related catheter infection. Saudi Journal of Kidney Diseases and Transplantation Vol. 26, no. 3 (May. 2015), pp.477-481.
https://search.emarefa.net/detail/BIM-567438
American Medical Association (AMA)
Khosroshahi, Hamid Tayyibi& Mahdi Bur, Husayn& Parkhideh, Sahar& Basmenji, Said& Khalil Zadah, Muhammad Rida& Tozihi, Majid. The effectiveness of systemic antibiotic therapy with and without ethanol-locked solution in the treatment of hemodialysis-related catheter infection. Saudi Journal of Kidney Diseases and Transplantation. 2015. Vol. 26, no. 3, pp.477-481.
https://search.emarefa.net/detail/BIM-567438
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 480-481
Record ID
BIM-567438