A study on the effects of inorganic lead on postnatal development of the motor cerebral cortex in albino rat
Other Title(s)
دراسة على تأثير الرصاص الغير عضوي على نمو القشرة الحركية للفأر الأبيض
Joint Authors
Jabr, Muhammad Abd al-Mughni
Muhammad, Muhammad al-Badri
Wahdan, Muhammad Hasan
Source
Issue
Vol. 26, Issue 2 (30 Apr. 2002), pp.133-145, 13 p.
Publisher
Assiut University Faculty of Medicine
Publication Date
2002-04-30
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Lead is a major environmental toxin.
Its toxicity causes haematdlogical, gastrointestinal and neurological dysfunctions.
In this study, there is a trial to elucidate how much inorganic lead affects the postnatal development of the motor area of the cerebrum.
Two groups of pregnant female albino rats were used; control and experimental.
The experimental rats were fed on chow, tap water, libitum and 1% lead carbonate from the first day of parturition.
The ages of the pups examined were 3,9,12,15 and 21 days postnatally for both groups.
The rats were anaesthesized with ether and decapitated.
The brains were extracted, histologically processed and stained with Einarson's Gallocyanine.
The results showed that the motor area of the control group has completed its maturation by the 21s' day postnatally which is the end of lactation.
This is indicated by the differentiation of the nerve cells, increased size of their cell bodies nuclei and Nissl's granules.
Also, there has been increased thickness ofthe cortex with decreased packing of the cells.
The experimental group showed, from day 9 postnatally, less distinct stratification of the motor cortex compared with the control group and delayed maturation of the cortical layers.
There was as well cavitation and neurocytic chromatolysis particularly at days 12 and 15.
Pericapillary space and capillary dilatation were seen.
American Psychological Association (APA)
Jabr, Muhammad Abd al-Mughni& Muhammad, Muhammad al-Badri& Wahdan, Muhammad Hasan. 2002. A study on the effects of inorganic lead on postnatal development of the motor cerebral cortex in albino rat. Assiut Medical Journal،Vol. 26, no. 2, pp.133-145.
https://search.emarefa.net/detail/BIM-57045
Modern Language Association (MLA)
Jabr, Muhammad Abd al-Mughni…[et al.]. A study on the effects of inorganic lead on postnatal development of the motor cerebral cortex in albino rat. Assiut Medical Journal Vol.26, No.2(April, 2002), pp.133-145.
https://search.emarefa.net/detail/BIM-57045
American Medical Association (AMA)
Jabr, Muhammad Abd al-Mughni& Muhammad, Muhammad al-Badri& Wahdan, Muhammad Hasan. A study on the effects of inorganic lead on postnatal development of the motor cerebral cortex in albino rat. Assiut Medical Journal. 2002. Vol. 26, no. 2, pp.133-145.
https://search.emarefa.net/detail/BIM-57045
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 143-145
Record ID
BIM-57045