Application op the proportional hazards model in the prognostic analysis of colon and gastrointestinal cancer data

Abstract EN

Some likely prognostic factors of the survival rates of certain colon and gastrointestinal cancer patients are analyzed in two separate studies, each involving Cox’s Proportional Hazards Model (PHM).

Each study uses the measured values of two serum protein-types: Carcinoembryonic Antigen (CEA) and Gamma-Glutamyl Transpeptidase (GGT), along with the respective ages of the patients, as the covariates under scrutiny.

Our results reveal age as insignificant in both cases, while only GGT for the colon-cancer and CEA for that of the gastrointestine appear influential on the survival times of the respective patients involved.

We illustrate the adequacy of the final forms of the model and highlight some of the reasons for its preference (over the parametric models) for this kind of analysis.