The outcome of in-vitro fertilization intracytoplasmic sperm injection (IVF ICSI)‎ cycles complicated by moderate-severe ovarian hyperstimulation syndrome (OHSS)‎

Abstract EN

-A retrospective study was used in the Fertility Clinic of the Department of Obstetrics & Gynecology, Tawam Hospi-tal, Al Ain, Abu Dhabi, United Arab Emirates to determine the outcome of'IVF/ICSI cycles complicated by OHSS.

Materials and Methods : In the period between January 1994and August2000, 3174IVF / lCSIcycleswerepetformed and 2918 cycles had reached embryo transfer.

564 women achieved pregnancy (19.

33 %).

92 women (3.15%) devel-oped moderate-severe OHSS and were hospitalized and their medical and IVF records were reviewed.

Supportive agement whilst waiting for the condition to resolve sponta-neously togetherwithfoUow-iip by ultrasound scan and blood tests was applied to all patients included in the study.

Pregtest was performed /7 days after ovum pick-up.

Results: Ninety-two women developed moderate-severe OHSS, 37 women of 'them had a clinical pregnancy (40.

2 %).

51.

4 % were singletons and 48.

6 % were multiple pregnan-cies; including 13 sets of twins, 4 sets (){triplets and one set of quadruplets.

The miscarriage rate was 32.

4 % and the spontaneousfetal reduction rate was 16.

6 %.

25 women con-tinned pregnancy (67.

6 %) ; eleven women had preterm de-livery (44 %), low birth weight rate was 44 % and take home baby rate was 59.4%.

The Cesarean section rate was 24 %.

Pregnancy-induced hypertension rate was only 8% and ges-tational diabetes 4 % There were cases of ectopic preg-nancy or placental abruption.

Conclusion : The pregnancy rate and the rate of mul-tiple pregnancy, miscarriage, prematurity, low birth weight and Cesarean section rate are significantly higher than those reported previously for pregnancies conceived with the use ofassisted reproductive techniques without the development OHSS.

The incidence other obstetric complications