The effect 0f Olea Europaea ethanolic extract on glucose tolerance and glucose uptake in hyperglycemic rats

Abstract EN

The effect of 200,400 and 800 mg/kg of ethanolic extract of Olea europaea leaves was evaluated in both glucose-loaded Wistar albino rats and in glucose uptake by using isolated rats hemidiaphgrams.

The effect of the three doses was studies 1, 2 and 4 hours after loading the fasting rats with glucose.

Their effects were compared to control rats administered with the vehicle and to a standard group administered with the standard drug Glibenclamide.

200 mg/kg of the extract was found to be the most effective dose in both models of experiments.