Anti bacterial activity of Psidium guajava and carthamus tinctoruis against respiratory tract infection

Abstract EN

The aim of this study was to enrich the information about the antimicrobial activity of some medicinal plants of the Sudan.

Also, to verify the claimed activity of certain Sudanese medicinal plants used in traditional medicine as antimicrobial agents, to subject these plants for further antimicrobial studies against clinical isolates, to determine their minimum inhibitory concentration (MICs) and to compare their activity with the commonly used antibacterial agents in the Sudan.

The chloroform, methanol and aqueous extract of Psidium guajava leaves (family : myrtacae) and Carthaumus tinctorius seeds (family : Asterceae) were screened for their antimicrobial activity against four standard bacteria : two gram positive (Staphylococcus aureus and Streptococcus pyogenes) and two gram negative (Klebsiella pneumoniae and Pseudomonas aeruginosa) using the cup plate agar diffusion method.

All six extracts were active against one or more of the four bacteria.

Four of these extracts inhibited the growth of all microorganisms.

Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumoniae were the most sensitive organisms to all extracts, while Streptococcus pyogenes showed less susceptibility.

The antibacterial activity of five reference drugs was determined against the tested four bacteria and their activity was compared to the activity of plants extracts