The effect of haemodialysis on prothrombin time, active partial thromboplastin time, and D dimer in late stage renal failure patients
Joint Authors
Abd Allah, Sana E.
Ahmad, Imad M.
Source
Sudan Medical Laboratory Journal
Issue
Vol. 2, Issue 2 (31 Dec. 2014), pp.27-35, 9 p.
Publisher
Omdurman Islamic University Faculty of Medical Laboratory
Publication Date
2014-12-31
Country of Publication
Sudan
No. of Pages
9
Main Subjects
Topics
Abstract EN
-Objectives Advanced renal failure (CRF) is referred to as end stage renal disease (ESRD).
Patients undergoing chronic haemodialysis treatment represent a high risk group for thromboembolic complications.
The aim of this study is to measure PT, APPT, and the concentration of D-dimer of end stage renal failure post haemodialysis and to determine the effect of duration of dialysis on PT, APTT and D-dimer concentration.
Methods 50 samples from patients with end stage renal failure and 25 as control group were collected.
PT and APTT were measured using automated coagulometer and D-dimer was measured by NycoCard D-dimer single test.
Results The mean of PT was 16.
1 sec compared to control group (12.
1sec).
The mean of APTT was 73.
8 sec while in the control group was 33.
6 sec.
The mean value of D-dimer concentration was 2.
26mg / L compared to 1.
52 mg / L in the control group.
According to the duration of dialysis PT in less than 4 years was 13.
9 seconds and was 14.
4 sec in more than 8 years.
APTT was found to be 62.
1 sec in < 4 years to 74.
9 sec and became 87.
5 sec in more than 8 years of dialysis and D-dimer was 1.
6 mg / L in < 4 years and 2.
6 mg / L in more than 8 years.
Conclusion The duration of hemodialysis finding elevated the coagulation parameters with increased duration of dialysis.
Treatment of anemia by rhEPO and iron supplement showed no effect in coagulation parameters
American Psychological Association (APA)
Abd Allah, Sana E.& Ahmad, Imad M.. 2014. The effect of haemodialysis on prothrombin time, active partial thromboplastin time, and D dimer in late stage renal failure patients. Sudan Medical Laboratory Journal،Vol. 2, no. 2, pp.27-35.
https://search.emarefa.net/detail/BIM-576329
Modern Language Association (MLA)
Abd Allah, Sana E.& Ahmad, Imad M.. The effect of haemodialysis on prothrombin time, active partial thromboplastin time, and D dimer in late stage renal failure patients. Sudan Medical Laboratory Journal Vol. 2, no. 2 (2014), pp.27-35.
https://search.emarefa.net/detail/BIM-576329
American Medical Association (AMA)
Abd Allah, Sana E.& Ahmad, Imad M.. The effect of haemodialysis on prothrombin time, active partial thromboplastin time, and D dimer in late stage renal failure patients. Sudan Medical Laboratory Journal. 2014. Vol. 2, no. 2, pp.27-35.
https://search.emarefa.net/detail/BIM-576329
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 34-35
Record ID
BIM-576329