MicroRNA applications in human cancers
Joint Authors
Lihita, Ula F.
Ibrahim, Jihan H.
Source
Suez Canal University Medical Journal
Issue
Vol. 17, Issue 2 (31 Dec. 2014), pp.75-85, 11 p.
Publisher
Suez Canal University Faculty of Medicine
Publication Date
2014-12-31
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Topics
Abstract EN
Over the last decade, a family of noncoding RNA molecules, including microRNA (miRNA) has been discovered.
MiRNAs have been implicated as key regulators of different cellular processes many of which are associated with cancer.
They contribute to the pathogenesis of human cancers; in addition, they may function as oncogenes or tumor suppressors in tumor development.
The unique expression profile of microRNAs in different types and subsets of tumor, besides to their possible identification in biological fluids indicate that they might serve as molecular biomarkers for cancer diagnosis, prognosis, and prediction of therapeutic responses.
However, they should achieve remarkable sensitivity and specificity, reproducibility and consistency between different studies.
Accumulating evidence suggests that alterations of miRNAs expression may ultimately yield new therapeutic strategies against cancer or at least guide clinical decision making.
The cur-rent review will give an overview on miRNAs, with a focus on their applications in human cancer diagnosis, prognosis, and therapy.
American Psychological Association (APA)
Lihita, Ula F.& Ibrahim, Jihan H.. 2014. MicroRNA applications in human cancers. Suez Canal University Medical Journal،Vol. 17, no. 2, pp.75-85.
https://search.emarefa.net/detail/BIM-576969
Modern Language Association (MLA)
Lihita, Ula F.& Ibrahim, Jihan H.. MicroRNA applications in human cancers. Suez Canal University Medical Journal Vol. 17, no. 2 (Dec. 2014), pp.75-85.
https://search.emarefa.net/detail/BIM-576969
American Medical Association (AMA)
Lihita, Ula F.& Ibrahim, Jihan H.. MicroRNA applications in human cancers. Suez Canal University Medical Journal. 2014. Vol. 17, no. 2, pp.75-85.
https://search.emarefa.net/detail/BIM-576969
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 82-85
Record ID
BIM-576969