Post renal transplantation tupulopathies in children : a 9-year experience at a tertiary car center
Joint Authors
al-Ibrahim, Alya
Sanjed, Sami A.
al-Abbas, Abbas
al-Sbban, Isam
al-Shaybani, Khalid
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 15, Issue 1 (28 Feb. 2004), pp.27-33, 7 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2004-02-28
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
Abstract EN
To evaluate the incidence of tubulopathies in the long-term follow-up of children post renal transplantation, we reviewed the records of 43 patients from 1987-1996.
There were 24 (56%) boys.
The age of patients at the time of transplant ranged from 2.7 to 15 years.
Eighteen children (78%) had transplantation from cadaver donors (CAD).
Thirty-two (74%) patients were transplanted in Saudi Arabia and 11(26%) were transplanted abroad.
Significant tubular dysfunction developed in 72% of patients.
Renal Tubular Acidosis (RTA) occurred in 23/43 (53%) patients.
The patients who received CAD grafts required higher mean dose of bicarbonate and longer duration of therapy compared to living related donors (LRD) recipients ( mean dose of 1.7 Vs 0.5 meq/kg/day and mean duration of 18 Vs 3 ½ months, respectively).
Hypophosphatemia of various degrees of severity (0.4-0.8 mmol/1) was detected in 12 (28%) patients.
Those who received CAD grafts required higher mean dose of phosphate and longer period of therapy than those who received LRD grafts.
Hypomagnesemia requiring supplemental magnesium therapy occurred in 4 (9%) patients, all received tacrolimus therapy.
In four patients with hypomagnesemia, this was mild and transient.
Hypokalemia was found in 5 (11.5%) patients; all had CAD grafts.
We conclude that tubulopathies were a frequent complication post renal transplantation in our population.
They were more severe in the patients who received CAD grafts.
However, the defects were controllable and transient.
American Psychological Association (APA)
al-Ibrahim, Alya& Sanjed, Sami A.& al-Abbas, Abbas& al-Sbban, Isam& al-Shaybani, Khalid. 2004. Post renal transplantation tupulopathies in children : a 9-year experience at a tertiary car center. Saudi Journal of Kidney Diseases and Transplantation،Vol. 15, no. 1, pp.27-33.
https://search.emarefa.net/detail/BIM-57880
Modern Language Association (MLA)
al-Ibrahim, Alya…[et al.]. Post renal transplantation tupulopathies in children : a 9-year experience at a tertiary car center. Saudi Journal of Kidney Diseases and Transplantation Vol. 15, no. 1 (Feb. 2004), pp.27-33.
https://search.emarefa.net/detail/BIM-57880
American Medical Association (AMA)
al-Ibrahim, Alya& Sanjed, Sami A.& al-Abbas, Abbas& al-Sbban, Isam& al-Shaybani, Khalid. Post renal transplantation tupulopathies in children : a 9-year experience at a tertiary car center. Saudi Journal of Kidney Diseases and Transplantation. 2004. Vol. 15, no. 1, pp.27-33.
https://search.emarefa.net/detail/BIM-57880
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 32-33
Record ID
BIM-57880