Synthesis of novel heterocyclic compounds via schiff bases

Abstract EN

In the present study a series of some four-, five-and seven-membered heterocyclic compounds have been synthesized by the reaetion of Schiff bases (1a, b) with chloroacetyl chloride, sodium azide, thioglycolic acid or various anhydrides to give azetidinone (2a, b), tetrazole (3a, b), thiazolidinone (4a, b) and 1,3-oxazepine derivatives (5-8a, b) respectively.

Schiff bases (1a, b)were prepared from the reaction of p-toluidine with aromatic aldehydes.

All synthesized compounds were characterized by physical properties and spectral data.