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Sickle cell disease and the kidney
Joint Authors
Niang, Abduh
Sene, Fatou S. Ndiaye
Fall, Seynabou
Diop, Therese Moreira
Diouf, Boucar
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 15, Issue 2 (30 Apr. 2004), pp.180-184, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2004-04-30
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Despite the frequency of sickle cell disease (SCD) in the West African population, the renal changes and outcome associated with it have been poorly characterized.
We retrospectively studied 22 renal patients; 19 heterozygous sickle cell trait (AS) and three homozygous (SS) evaluated between 1996-2002.
The mean age was 43 years (range from 19-69 years).
The observed nephropathies included chronic glomerulonephritis (CGN) in eight (36.3%) cases, advanced chronic renal failure (CRF) in seven (31.8%), chronic tubulointerstitial nephropathy (CTIN) in four cases (18.1%), post-infectious acute glomerulonephritis (AGN) in two(9.1%) cases and pregnancy related nephropathy in one (4.5%) case.
Renal biopsy was performed in five (22.7%) patients (three AS and two SS patients); the findings included membrano proliferative glomerulonephritis (MPGN), CTIN, focal and segmental glomerulosclerosis (FSGS) and membranous glomerulonephritis.
We conclude that there are various renal abnormalities associated with SCD and optimal management needs early diagnosis and multidisciplinary follow-up.
American Psychological Association (APA)
Niang, Abduh& Diouf, Boucar& Sene, Fatou S. Ndiaye& Fall, Seynabou& Diop, Therese Moreira. 2004. Sickle cell disease and the kidney. Saudi Journal of Kidney Diseases and Transplantation،Vol. 15, no. 2, pp.180-184.
https://search.emarefa.net/detail/BIM-58069
Modern Language Association (MLA)
Niang, Abduh…[et al.]. Sickle cell disease and the kidney. Saudi Journal of Kidney Diseases and Transplantation Vol. 15, no. 2 (Apr. 2004), pp.180-184.
https://search.emarefa.net/detail/BIM-58069
American Medical Association (AMA)
Niang, Abduh& Diouf, Boucar& Sene, Fatou S. Ndiaye& Fall, Seynabou& Diop, Therese Moreira. Sickle cell disease and the kidney. Saudi Journal of Kidney Diseases and Transplantation. 2004. Vol. 15, no. 2, pp.180-184.
https://search.emarefa.net/detail/BIM-58069
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 183-184
Record ID
BIM-58069