Leptin and insulin resistance in obese children
Joint Authors
Tahir, Nur T.
Ahmad, Hind S.
Ghazi, al-Mutasim Billah A.
Source
al-Kindy College Medical Journal
Issue
Vol. 10, Issue 2 (31 Dec. 2014), pp.35-39, 5 p.
Publisher
University of Baghdad al-Kindi College of Medicine
Publication Date
2014-12-31
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background : Insulin resistance (IR) is the primary metabolic disorder associated with obesity.
Obesity is a growing worldwide health problem affecting both adults and children.
Objectives: To determine the association between leptin and IR, and to identify the ratio of fasting glucose/leptin (G / L) and insulin/leptin ( I / L) as a new simple method for the detection of IR in obese children.
Methods: This study was done in the National Diabetic Center/ AL-Mustansiriya University during the period from May 2013 until the end of October 2013.
Fasting blood glucose (FBG), serum insulin, leptin, and lipid profile were measured in 52 obese children (24 children with IR and 28 without IR); their age range was (5-15) years, they were compared with 38 healthy children as a control group.
Results: Means of FBG, insulin, leptin, total cholesterol (TC), triacylglycerol (TAG), low density lipoprotein cholesterol (LDL-C), and non high density lipoprotein cholesterol (non HDL-C) were significantly increased in obese children with IR as compared in children without IR, (P<0.05), while there was a significant decrease in serum level of high density lipoprotein cholesterol (HDL-C) in obese children with IR when compared with obese children without IR, (P=0.001).
There was a decrease in the ratio of G/L and an increase in the ratio of I/L in obese children with IR, but it was not significant.
A significant positive
American Psychological Association (APA)
Tahir, Nur T.& Ahmad, Hind S.& Ghazi, al-Mutasim Billah A.. 2014. Leptin and insulin resistance in obese children. al-Kindy College Medical Journal،Vol. 10, no. 2, pp.35-39.
https://search.emarefa.net/detail/BIM-580780
Modern Language Association (MLA)
Tahir, Nur T.…[et al.]. Leptin and insulin resistance in obese children. al-Kindy College Medical Journal Vol. 10, no. 2 (2014), pp.35-39.
https://search.emarefa.net/detail/BIM-580780
American Medical Association (AMA)
Tahir, Nur T.& Ahmad, Hind S.& Ghazi, al-Mutasim Billah A.. Leptin and insulin resistance in obese children. al-Kindy College Medical Journal. 2014. Vol. 10, no. 2, pp.35-39.
https://search.emarefa.net/detail/BIM-580780
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 38-39
Record ID
BIM-580780