Preparation and study antibacterial activity of a new polymer

Abstract EN

This search is including preparation of a new N-substitution maleimide of homopolymer and copolymer by five steps and study antibacterial activity.

1.

preparation of azo compound by reaction of the sulfadiazine with 3-aminophenol to produced [A] 2.

preparation of the amic acid by reaction between [A] compound with malic anhydride to produced[B]compound.

3.

preparation of the monemer [N-substitution maleimide] by closed the ring and convert the [B]compound to [C] compound by access the acetic anhydride and sodium acetate.

4.

preparation of the homopolymer by reaction[C] compound with AIBN as initiator and DMF as a solvent, to produced [D]compound.

5.

preparation of the copolymer by reaction[C] compound with acrylamide in found AIBN as initiator and DMF as a solvent, to produced [C]compound.

FT-IR and 1H NMR Spectra and C.H.N.S.

analysis which reveals the confirmation of these compounds in good agreement.

The last step includes the study antibacterial activity of some prepared compounds against two types of bacteria : Staphylococcus aureus (Gram positive) and Pseudomonas aeruginosa (Gram negative).