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Assessment of the immunohistochemical expression of EBV in oral lichen planus
Joint Authors
al-Tahan, Tania Abd Allah
Majid, Ahlam Hamid
Source
Journal of Baghdad College of Dentistry
Issue
Vol. 27, Issue 2 (30 Jun. 2015), pp.98-100, 3 p.
Publisher
University of Baghdad College of Dentistry
Publication Date
2015-06-30
Country of Publication
Iraq
No. of Pages
3
Main Subjects
Topics
Abstract AR
الخلفیة : یعد الحزاز الفموي المنبسط من أحد الأمراض المناعیة المزمنة غیر معروفة الأسباب.
و یفترض فایروس ال EBV كأحد الأسباب المرضیة.
تھدف الدراسة إلى تقییم الظھور النسیج المناعي لفایروس EBVفي عینات الحزاز الفموي المنبسط.
طرق البحث: تم تقییم الظھور الكیمیائي النسیجي المناعي لفایروس EBV عن طریق الاجسام المضادة في ثلاثین عینة من الحزاز الفموي المنبسط محفوظة في الفورمالین و مغمورة بشمع البارافین.
النتائج: أظھرت الدراسة وجود فایروس EBV في 46,6 % من الحالات المدروسة.
لم یتم إيجاد أي علاقة لظھور الفایروس مع المتغیرات السریریة باستثناء وجوده بشكل اكبر في الإناث وبدلالة معنویة.
الاستنتاجات: یتواجد فایروس EBVبشكل ملحوظ في الحزاز الفموي المنبسط.
من الممكن إجراء دراسات أخرى لتأكید دور الفایروس في نشأة المرض.
Abstract EN
Background: Oral lichen planus (OLP) is a chronic immunologic disease.
The etiology of OLP is unknown, viral antigens (for example EBV) have been proposed as etiologic agents.
OLP may get transformation to malignancy so research on the presence of these in OLP lesions seems to be necessary.
The aim of this study was to evaluate EBV expression immunohistochemically in OLP.
Materials and Methods: Tissue specimens of 30 formalin fixed, paraffin-embedded tissue Blocks histologically diagnosed oral lichen planus was performed to evaluate EBV expression.
Results: Expression of EBV was detected in epithelium of (46.6%) in the study samples in (OLP).
no statistically significant correlation was found with clinical parameters except for a significantly higher expression in females.
Conclusions: Epstein Barr viruses were present in considerable amounts in oral lichen planus.
Taking into account the potential of viruses in OLP proving or disapproving or etiological role of viruses in OLP is continuously need to be examined in further studies.
American Psychological Association (APA)
al-Tahan, Tania Abd Allah& Majid, Ahlam Hamid. 2015. Assessment of the immunohistochemical expression of EBV in oral lichen planus. Journal of Baghdad College of Dentistry،Vol. 27, no. 2, pp.98-100.
https://search.emarefa.net/detail/BIM-590796
Modern Language Association (MLA)
al-Tahan, Tania Abd Allah& Majid, Ahlam Hamid. Assessment of the immunohistochemical expression of EBV in oral lichen planus. Journal of Baghdad College of Dentistry Vol. 27, no. 2 (Jun. 2015), pp.98-100.
https://search.emarefa.net/detail/BIM-590796
American Medical Association (AMA)
al-Tahan, Tania Abd Allah& Majid, Ahlam Hamid. Assessment of the immunohistochemical expression of EBV in oral lichen planus. Journal of Baghdad College of Dentistry. 2015. Vol. 27, no. 2, pp.98-100.
https://search.emarefa.net/detail/BIM-590796
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 100
Record ID
BIM-590796