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Time-related salivary cathepsin b levels and periodontal status in different orthodontic force magnitudes
Joint Authors
Yassir, Yassir A.
al-Judy, Hikmat J.
Salih, Hara S. Muhammad
Ahmad, Maha Abdul Aziz
Source
Journal of Baghdad College of Dentistry
Issue
Vol. 27, Issue 2 (30 Jun. 2015), pp.115-122, 8 p.
Publisher
University of Baghdad College of Dentistry
Publication Date
2015-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
Abstract EN
Background: Biologically active substances, such as Cathepsin B (CAB) which is a lysosomalcystein protease may be involved in periodontal metabolism in the degradation of organic bone matrix containing collagen fibers in response to mechanical stress from orthodontic appliance.
The aims of study were to determine and compare salivary levels of CAB, pH as well as clinical periodontal parameters (Plaque index PLI and gingival index GI) with different orthodontic force magnitudes at different time intervals.
Materials and methods: A twenty-four patients (both gender) with age range (17-23) years had Angle's Class II division 1 malocclusion with GI <0.5 enrolled in this study.
The level of salivary CAB and pH, in addition to the clinical periodontal parameters (PLI and GI) were measured before (baseline), 1 hour (1H), 1 day (1D), 1week (1W), 2 weeks (2W) and 3 weeks (3W) after fixed orthodontic appliance placement with different forces applied to the teeth (F1 (40 gm), F2 (60 gm) and F3 (80 gm)).
Results: The highest mean concentration of salivary CAB was (12.057) at F1 in 1D visit with highly significant differences among the visits as well as among the forces (p≤0.05).
Weak correlations were revealed between all pairs of forces as well as between each visit with the baseline visit about salivary CAB except the strong negative correlations between F1 with F3 at 3W and baseline with 3W visits at F3.
Maintenance of good oral hygiene during the study period demonstrated that the highest mean values of PLI and GI were (0.2) and (0.25) respectively, in addition to the non-significant differences regarding pH among the visits.
Conclusion: The concentration of salivary CAB was increased following fixed orthodontic appliance insertion.
The very light continuous orthodontic force could produce significant increase of this enzyme activity and give enough effectiveness to produce tooth movement as compared to the higher forces.
American Psychological Association (APA)
Ahmad, Maha Abdul Aziz& Salih, Hara S. Muhammad& Yassir, Yassir A.& al-Judy, Hikmat J.. 2015. Time-related salivary cathepsin b levels and periodontal status in different orthodontic force magnitudes. Journal of Baghdad College of Dentistry،Vol. 27, no. 2, pp.115-122.
https://search.emarefa.net/detail/BIM-590925
Modern Language Association (MLA)
Ahmad, Maha Abdul Aziz…[et al.]. Time-related salivary cathepsin b levels and periodontal status in different orthodontic force magnitudes. Journal of Baghdad College of Dentistry Vol. 27, no. 2 (Jun. 2015), pp.115-122.
https://search.emarefa.net/detail/BIM-590925
American Medical Association (AMA)
Ahmad, Maha Abdul Aziz& Salih, Hara S. Muhammad& Yassir, Yassir A.& al-Judy, Hikmat J.. Time-related salivary cathepsin b levels and periodontal status in different orthodontic force magnitudes. Journal of Baghdad College of Dentistry. 2015. Vol. 27, no. 2, pp.115-122.
https://search.emarefa.net/detail/BIM-590925
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 121-122
Record ID
BIM-590925