First bahraini adolescent with anti-Nmdar-Ab encephalitis
Joint Authors
al-Musallamni, Ahwd
Mahmud, Fatimah
Source
Issue
Vol. 24, Issue 1 (30 Jun. 2015), pp.1-7, 7 p.
Publisher
Publication Date
2015-06-30
Country of Publication
Qatar
No. of Pages
7
Main Subjects
Topics
Abstract EN
Anti-N-methyl-D-aspartate-receptor (NMDA-R) encephalitis is a new autoimmune, often paraneoplastic disorder that presents with complex neuropsychiatric symptoms.
It was first described in 2007 by Dalmau et al.
Our patient presented with headache, behavioral changes and then seizures with hallucinations.
She was initially misdiagnosed to have schizophrenia and was prescribed antipsychotics.
She deteriorated and developed further seizures with hypoventilation and choreoathetosis.
Her blood investigations were positive for mycoplasma IGM.
Her CSF studies showed high white cell counts, predominantly lymphocytes, and high anti-NMDA-R titre.
Her brain MRI scans showed high T2 and FLAIR intensities in the grey and white matter of the left cerebellar hemisphere suggestive of acute disseminated encephalomyelitis.
She responded to treatment with antibiotics, multiple antiepileptics, steroids and needed five sessions of plasmapheresis.
There was no underlying malignancy on repeated scanning of the abdomen.
She needed around one year for full recovery with intensive rehabilitation.
The objective of this paper was to highlight the occurrence of this fairly new, challenging, easily missed, not-so-rare form of encephalitis often occurring in the absence of fever.
American Psychological Association (APA)
al-Musallamni, Ahwd& Mahmud, Fatimah. 2015. First bahraini adolescent with anti-Nmdar-Ab encephalitis. Qatar Medical Journal،Vol. 24, no. 1, pp.1-7.
https://search.emarefa.net/detail/BIM-591778
Modern Language Association (MLA)
al-Musallamni, Ahwd& Mahmud, Fatimah. First bahraini adolescent with anti-Nmdar-Ab encephalitis. Qatar Medical Journal Vol. 24, no. 1 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-591778
American Medical Association (AMA)
al-Musallamni, Ahwd& Mahmud, Fatimah. First bahraini adolescent with anti-Nmdar-Ab encephalitis. Qatar Medical Journal. 2015. Vol. 24, no. 1, pp.1-7.
https://search.emarefa.net/detail/BIM-591778
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 6-7
Record ID
BIM-591778