Serum Cystatin-C and beta 2-microglobulin as accurate markers in the early diagnosis of kidney injury in neonates : a single center study
Joint Authors
al-Frargy, Muhammad S.
Husayn, Mukhtar A.
al-Rifai, Ahmad M.
Id, Riham
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 26, Issue 4 (31 Aug. 2015), pp.712-717, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2015-08-31
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
- Children
- Kidneys
- Diseases
- Medical diagnosis
- Complications(Medicine)
- Blood serum
- Infants
- Kidney failure
- Cystatin C
Abstract EN
Early detection of kidney injury in neonates is very important for appropriate management and prevention of serious complications; however, commonly used detectors as creatinine and blood urea nitrogen (BUN) do not directly reflect early renal cell injury.
Serum cystatin-C (Cys-C) and beta 2-microglobulin (Β2M), serum creatinine and BUN were assessed in 20 neonates who developed renal impairment after admission to the neonatal intensive care unit and 10 healthy neonates.
The means of serum Cys-C, Β2M and creatinine on Day 1 of admission in the cases and control groups were 2.15 ± 0.52 vs 0.45 ± 0.19, 7.18 ± 2.36 vs 1.92 ± 0.41 and 0.81 ± 0.07 vs 0.53 ± 0.20, respectively, with P-value <0.05 in only Cys-C and Β2M.
We conclude that serum Cys-C and Β2M are suggested as simple and accurate markers for the early diagnosis of kidney injury in neonates than serum creatinine.
American Psychological Association (APA)
al-Frargy, Muhammad S.& al-Rifai, Ahmad M.& Id, Riham& Husayn, Mukhtar A.. 2015. Serum Cystatin-C and beta 2-microglobulin as accurate markers in the early diagnosis of kidney injury in neonates : a single center study. Saudi Journal of Kidney Diseases and Transplantation،Vol. 26, no. 4, pp.712-717.
https://search.emarefa.net/detail/BIM-592703
Modern Language Association (MLA)
al-Frargy, Muhammad S.…[et al.]. Serum Cystatin-C and beta 2-microglobulin as accurate markers in the early diagnosis of kidney injury in neonates : a single center study. Saudi Journal of Kidney Diseases and Transplantation Vol. 26, no. 4 (Jul. / Aug. 2015), pp.712-717.
https://search.emarefa.net/detail/BIM-592703
American Medical Association (AMA)
al-Frargy, Muhammad S.& al-Rifai, Ahmad M.& Id, Riham& Husayn, Mukhtar A.. Serum Cystatin-C and beta 2-microglobulin as accurate markers in the early diagnosis of kidney injury in neonates : a single center study. Saudi Journal of Kidney Diseases and Transplantation. 2015. Vol. 26, no. 4, pp.712-717.
https://search.emarefa.net/detail/BIM-592703
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 716-717
Record ID
BIM-592703