Synthesis and characterization of some 1, 3, 4-oxadiazolederivatives and new cyclic imides from creatinine
Other Title(s)
تحضير و تشخيص بعض مشتقات 1، 3، 4-اوكسادايازول و ايمايدا تحلقية جديدة من الكرياتينين
Joint Authors
Kalaf, Muna Ismal
Hashim, Usamah Sadiq
Source
Issue
Vol. 56, Issue 2A (31 Mar. 2015), pp.921-941, 21 p.
Publisher
University of Baghdad College of Science
Publication Date
2015-03-31
Country of Publication
Iraq
No. of Pages
21
Main Subjects
Topics
Abstract EN
A series of new 1,3,4- oxadiazole derivatives and cyclic Imides containing Creatinine heterocyclic molecule were prepared via following method:first step included Synthesis of amic acid from reaction between different cyclic anhydrides with Creatinine which subsequently dehydrated to the corresponding imide via treatment with acetic anhydride and anhydrous sodium acetate,.then,second step was tratedamic acid with Thionyl chloride producing acid chloride which on amination with hydrazine hydrate in thierd step and the last turn to 1,3,4-oxadiazole derivatives by condensation reaction with Phosphorous Oxychloride(POCl3) and different benzoic acids.
Cyclization to 1, 3, 4-Oxadiazole derivatives.
Antibacterial activity of some prepared new compounds against two types of bacteria were evaluated and result showed the new exhibit good moderate antibacterial activity.Prepared compounds were elucidated on the basis FT-IR,1H-NMR and MASS spectro data which agreed with the proposed structures.
American Psychological Association (APA)
Kalaf, Muna Ismal& Hashim, Usamah Sadiq. 2015. Synthesis and characterization of some 1, 3, 4-oxadiazolederivatives and new cyclic imides from creatinine. Iraqi Journal of Science،Vol. 56, no. 2A, pp.921-941.
https://search.emarefa.net/detail/BIM-593515
Modern Language Association (MLA)
Kalaf, Muna Ismal& Hashim, Usamah Sadiq. Synthesis and characterization of some 1, 3, 4-oxadiazolederivatives and new cyclic imides from creatinine. Iraqi Journal of Science Vol. 56, no. 2A (2015), pp.921-941.
https://search.emarefa.net/detail/BIM-593515
American Medical Association (AMA)
Kalaf, Muna Ismal& Hashim, Usamah Sadiq. Synthesis and characterization of some 1, 3, 4-oxadiazolederivatives and new cyclic imides from creatinine. Iraqi Journal of Science. 2015. Vol. 56, no. 2A, pp.921-941.
https://search.emarefa.net/detail/BIM-593515
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 940-941
Record ID
BIM-593515