Hereditary angioedema a literature review and national management guidelines

Abstract EN

Background : Hereditary angioedema, a rare and potentially life-threatening condition, is the result of a defect in the C1 esterase inhibitor.

Primary care physicians should be familiar with this condition to avoid complications and improve quality of care.

Methods : We present two cases of hereditary angioedema followed by a discussion based on a literature review of the recent guidelines and advances in this condition.

Objectives : To highlight the clinical aspects, diagnosis and treatment of this condition and propose a practical local management based on the available medication.

Conclusion : Hereditary angioedema management is still evolving.

More efforts should be made concerning the drug therapy which is very costly and not available worldwide.