Cutaneous vacuities and asthenia in a patient with HCV-related chronic liver disease without detectable serum cryoglobulinemia
Other Title(s)
التهاب الأوعية الجلدية و الوهن لمريضة تعاني من مرض الكبد المزمن المرتبط بالتهاب الكبد الوبائي ج دون وجود للجلوبيولينات الباردة في المصل
Author
al-Husayki, Ibrahim Gharm Allah
Source
Journal of King Abdulaziz University : Medical Sciences
Issue
Vol. 22, Issue 1 (31 Mar. 2015), pp.39-43, 5 p.
Publisher
King Abdulaziz University Scientific Publishing Center
Publication Date
2015-03-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract AR
الغرض من ھذا البحث إيجاد قوس من الدرجة الخامسة في المستوى الإسقاطي q = 29.31, PG(2,q)، ذات زمرة مثبتة من النوع زمرة داھیدرل من الدرجة الخامسة D5 و أقواس من الدرجة السادسة و العاشرة ذات زمرة مثبته من نوع الزمرة المتناوبة من الدرجة الخامسة A5 و من ثم دراسة تأثیر D5 و A5 في نقاط المستوى الإسقاطي و كذلك، إيجاد بنتاستام ذات نقاط قطریة على استقامة واحدة.
Abstract EN
This paper reports a case of 47-year-old lady with Hepatitis C virus-related chronic liver disease who presented with asthenia and purpuric skin eruption involving her lower limbs.
Punched skin biopsy from one of those lesions was consistent with small vessels vasculitis.
Although Hepatitis c virus-related vasculitis is usually associated with cryoglobulinemia, in the present case the serum cryoglobulins were not detected on three different occasions.
Moreover, testing for indirect biomarkers for mixed cryoglobulinemia (rheumatoid factor and low complements) were negative.
The patient treated with PEG-interferon alfa-2a plus ribavirin for 24 weeks and showed partial virological response.
However, after two months from the start of treatment the cutaneous lesion disappeared completely with marked improvement of asthenia and remained asymptomatic during a follow-up period of 12 months after the antiviral treatment stopped.
This case highlights that patients with Hepatitis c virus may have cutaneous vasculitis without detectable serum Cryoglobulins.
combination therapy with PEG-interferon alfa-2a and ribavirin is an efèctive treatment approach for such patients.
American Psychological Association (APA)
al-Husayki, Ibrahim Gharm Allah. 2015. Cutaneous vacuities and asthenia in a patient with HCV-related chronic liver disease without detectable serum cryoglobulinemia. Journal of King Abdulaziz University : Medical Sciences،Vol. 22, no. 1, pp.39-43.
https://search.emarefa.net/detail/BIM-599135
Modern Language Association (MLA)
al-Husayki, Ibrahim Gharm Allah. Cutaneous vacuities and asthenia in a patient with HCV-related chronic liver disease without detectable serum cryoglobulinemia. Journal of King Abdulaziz University : Medical Sciences Vol. 22, no. 1 (2015), pp.39-43.
https://search.emarefa.net/detail/BIM-599135
American Medical Association (AMA)
al-Husayki, Ibrahim Gharm Allah. Cutaneous vacuities and asthenia in a patient with HCV-related chronic liver disease without detectable serum cryoglobulinemia. Journal of King Abdulaziz University : Medical Sciences. 2015. Vol. 22, no. 1, pp.39-43.
https://search.emarefa.net/detail/BIM-599135
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 41-42
Record ID
BIM-599135