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Intravenous immunoglobulin-resistant Kawasaki disease treated with pulsed doses of methylprednisolone
Joint Authors
Qaqish, Khalid S.
al-Dhahiri, Watfa S.
Bin Uthman, Salim
Source
Issue
Vol. 30, Issue 1 (31 Mar. 2008), pp.1-5, 5 p.
Publisher
King Hamad University Hospital
Publication Date
2008-03-31
Country of Publication
Bahrain
No. of Pages
5
Main Subjects
Abstract EN
Kawasaki Disease (KD) is usually treated with high doses of Intravenous Immunogobulin (IVIG) and aspirin.
However, 10-15% of children with KD are resistant to IVIG therapy.
Corticosteroid therapy remains a controversial alternative in such cases.
We report a case of a four year old boy with KD who was resistant to treatment with high dose IVIG (2 courses of 2g / Kg/day) and aspirin (80mg / Kg / day) and was subsequently treated with pulsed doses of Methylprednisolone (30mg / Kg / day) for three days.
The child apparently responded with rapid defervescence, improvement in clinical symptoms, normalization of acute-phase reactants and no progression of coronary artery dilatation or any adverse effects.
Pulsed doses of Methyl prednisolone therapy appeared to be a safe and effective treatment for this particular IVIG–resistant KD patient.-
American Psychological Association (APA)
Qaqish, Khalid S.& al-Dhahiri, Watfa S.& Bin Uthman, Salim. 2008. Intravenous immunoglobulin-resistant Kawasaki disease treated with pulsed doses of methylprednisolone. Bahrain Medical Bulletin،Vol. 30, no. 1, pp.1-5.
https://search.emarefa.net/detail/BIM-601554
Modern Language Association (MLA)
Qaqish, Khalid S.…[et al.]. Intravenous immunoglobulin-resistant Kawasaki disease treated with pulsed doses of methylprednisolone. Bahrain Medical Bulletin Vol. 30, no. 1 (Mar. 2008), pp.1-5.
https://search.emarefa.net/detail/BIM-601554
American Medical Association (AMA)
Qaqish, Khalid S.& al-Dhahiri, Watfa S.& Bin Uthman, Salim. Intravenous immunoglobulin-resistant Kawasaki disease treated with pulsed doses of methylprednisolone. Bahrain Medical Bulletin. 2008. Vol. 30, no. 1, pp.1-5.
https://search.emarefa.net/detail/BIM-601554
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 4-5
Record ID
BIM-601554