Red cell alloimmunization in thalassaemia patients
Joint Authors
Bashawri, Layla A. M.
Ahmad, Malik S.
al-Fawwaz, Najla
al-Qatary, Ahlam A. K.
Ahmad, Mirghani Ali
Source
Issue
Vol. 27, Issue 2 (30 Jun. 2005), pp.1-6, 6 p.
Publisher
King Hamad University Hospital
Publication Date
2005-06-30
Country of Publication
Bahrain
No. of Pages
6
Main Subjects
Topics
Abstract EN
Objectives : To determine the frequency of red cell alloantibodies in a thalassaemia patient and to identify the common alloantibodies.
Methods : A retrospective review of blood bank records for all thalassaemia patients.
The records included, request received for blood group typing, antibody screen, antibody identification and cross-matching during the period between October 1st, 1997 to September 30, 2002.
The history of blood transfusion was reviewed and the frequency rate for alloantibodies was determined.
Results : Out of 76 thalassemic patients, nine (11.8 %) had developed alloantibodies.
Alloantibodies detected include: nonspecific antibodies 3 (33.3 %), anti E and nonspecific 2 (22.2 %), anti-K together with non specific antibodies 1 (11.1%), anti-E 1 (11.1%), anti E together with anti K and nonspecific alloantibodes 1 (11.1%), anti-Lea 1 (11.1%).
Conclusion : Red cell alloantibodies developed in 11.8 % of thalassemic patients.
The most common alloantibodies were Rhesus and Kell antibodies, which are present in 33.3 % and 22.2 % of these patients respectively.
Alloimmunization is not an uncommon problem facing blood banks and finding compatible units for regularly transfused thalassemic patients may be very difficult.
In order to reduce alloimmunization a policy for performing extended red cell phenotyping on these
American Psychological Association (APA)
Bashawri, Layla A. M.& Ahmad, Malik S.& al-Fawwaz, Najla& al-Qatary, Ahlam A. K.& Ahmad, Mirghani Ali. 2005. Red cell alloimmunization in thalassaemia patients. Bahrain Medical Bulletin،Vol. 27, no. 2, pp.1-6.
https://search.emarefa.net/detail/BIM-602978
Modern Language Association (MLA)
Bashawri, Layla A. M.…[et al.]. Red cell alloimmunization in thalassaemia patients. Bahrain Medical Bulletin Vol. 27, no. 2 (Jun. 2005), pp.1-6.
https://search.emarefa.net/detail/BIM-602978
American Medical Association (AMA)
Bashawri, Layla A. M.& Ahmad, Malik S.& al-Fawwaz, Najla& al-Qatary, Ahlam A. K.& Ahmad, Mirghani Ali. Red cell alloimmunization in thalassaemia patients. Bahrain Medical Bulletin. 2005. Vol. 27, no. 2, pp.1-6.
https://search.emarefa.net/detail/BIM-602978
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 4-5
Record ID
BIM-602978