Laryngeal amyloidosis

Abstract EN

Localized amyloidosis of the head and neck is a rare and benign disease of unknown nature.

It affects males slightly more than females, between 40 – 60 years of age.

Laryngeal amyloidosis is a very rare disease, accounting for less than 1% of all benign laryngeal tumors.

It is characterized by the deposition of a homogeneous eosinophilic extra-cellular material in the laryngeal tissues, this material is of a protein in nature.

We report a female, middle aged, who presented with dysphonia and was found to have an isolated laryngeal amyloidosis.

The report discusses the presentation, diagnosis, treatment with endoscopic carbon dioxide laser, the nature of the recurrence of the disease, and the need for the long term follow up to rule out any evidence of local recurrence and / or development of systemic involvement.