![](/images/graphics-bg.png)
Familial mediterranean fever and renal disease
Author
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 14, Issue 3 (30 Jun. 2003), pp.378-385, 8 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2003-06-30
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Topics
Abstract EN
Familial Mediterranean Fever (FMF) is a genetic disorder frequently diagnosed among the Arabs.
It is also prevalent among Jews, Armenians and Turks.
The clinical picture consists of febrile and painful attacks such as joint or chest pain that differ in quality across patients and even within the same patient.
The gene responsible for FMF, MEFV, has been cloned and mutations were identified within its coding sequence.
It encodes a protein that is expected to be a down regulator of inflammation.
The major renal involvement in FMF is the occurrence of amyloidosis that primarily affects the kidneys causing proteinuria and ending in death from renal failure.
It can be treated by dialysis and renal transplantation, but can be prevented by a daily regimen of colchicine.
Other renal manifestations of FMF are discussed.
American Psychological Association (APA)
al-Shanti, Hatim I.. 2003. Familial mediterranean fever and renal disease. Saudi Journal of Kidney Diseases and Transplantation،Vol. 14, no. 3, pp.378-385.
https://search.emarefa.net/detail/BIM-60426
Modern Language Association (MLA)
al-Shanti, Hatim I.. Familial mediterranean fever and renal disease. Saudi Journal of Kidney Diseases and Transplantation Vol. 14, no. 3 (Aug. 2003), pp.378-385.
https://search.emarefa.net/detail/BIM-60426
American Medical Association (AMA)
al-Shanti, Hatim I.. Familial mediterranean fever and renal disease. Saudi Journal of Kidney Diseases and Transplantation. 2003. Vol. 14, no. 3, pp.378-385.
https://search.emarefa.net/detail/BIM-60426
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 383-385
Record ID
BIM-60426