Prevalence of alkaptonuria in South of Jordan

Abstract EN

Objectives : The aim of this study is to analyze the incidence of alkaptonuria in south of Jordan and to point out its preval e nct~ among .Jordanians at this region Materials and l\-1ethods : This study was b<:ased on screening of first and second degree relatives of three already diagnosed patient~, and random scn!ening of 300 persons from both sexes "'rith the age group from 6-18 years, living in Al-Taybah 10 kilometers from Peh·a.

Results: Alkaptonul'ia was found in 2 cases among relatives of the affected patients.

Random screening reveals the p1·esence of 4 cases.

Conclusion : Even though AJkaptonw·ia is a rare metabolic disorder worldwide, we have a high incidence in south of Jordan, with an unusual association with epilepsy in one patient.

Further studies are necessary to point out the incidence of Alkaptonuria in Jordan ; and there must be propea· methods to contr·ol the progr·ession of this disonler .