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Visceral leishmaniasis in a patient with sicca syndrome and nephropathy
Joint Authors
Bin Maiz, Hadi
Kaaroud, Hayet
Beji, Sumayyah
Bin Musa, Fatimah
Bin Abd Allah, Tayyib
Mhibik, S.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 14, Issue 4 (31 Aug. 2003), pp.526-529, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2003-08-31
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
- Patients
- Salivary glands
- Kidneys
- Diseases
- Leishmaniasis
- Complications(Medicine)
- Visceral leishmaniasis
- Sjogren's syndrome
Abstract EN
A 63-year-old woman presented with severe volume depletion and pre-renal azotemia.
She had xerostomia, xerophthalmia and cervical lymphadenopathy.
Urine examination revealed proteinuria, hematuria and glycosuria.
Laboratory studies, after volume repletion, revealed hyper-gammaglobulinemia.
Renal biopsy showed interstitial nephropathy and salivary-gland biopsy showed glandular atrophy and diffuse fibrosis.
Diagnosis of leishmaniasis was established by bone marrow examination and serology.
The patient was treated with pentavalent antimonial (Glucantime) with an excellent response.
The treatment, however, had to be interrupted because of transient nephrotoxicity.
After a break of four weeks, the antimonial was reinstituted with no more side effects.
Both the sicca syndrome and the nephropathy responded very well to the treatment at nine months follow-up.
In this case the presentation of visceral leishmaniasis was atypical, probably because of the partially suppressed immunity.
The clue to the diagnosis was the polyclonal hypergammaglobulinemia.
American Psychological Association (APA)
Kaaroud, Hayet& Mhibik, S.& Beji, Sumayyah& Bin Musa, Fatimah& Bin Abd Allah, Tayyib& Bin Maiz, Hadi. 2003. Visceral leishmaniasis in a patient with sicca syndrome and nephropathy. Saudi Journal of Kidney Diseases and Transplantation،Vol. 14, no. 4, pp.526-529.
https://search.emarefa.net/detail/BIM-60492
Modern Language Association (MLA)
Kaaroud, Hayet…[et al.]. Visceral leishmaniasis in a patient with sicca syndrome and nephropathy. Saudi Journal of Kidney Diseases and Transplantation Vol. 14, no. 4 (Aug. 2003), pp.526-529.
https://search.emarefa.net/detail/BIM-60492
American Medical Association (AMA)
Kaaroud, Hayet& Mhibik, S.& Beji, Sumayyah& Bin Musa, Fatimah& Bin Abd Allah, Tayyib& Bin Maiz, Hadi. Visceral leishmaniasis in a patient with sicca syndrome and nephropathy. Saudi Journal of Kidney Diseases and Transplantation. 2003. Vol. 14, no. 4, pp.526-529.
https://search.emarefa.net/detail/BIM-60492
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 528-529
Record ID
BIM-60492