Comparative study between Nigella Sativa and Ziziphus Spina-Christi effectiveness on skin a superficial burn healing in rabbits

Abstract EN

The present study to evaluate the third degree burn involved all skin layers (full-thickness burns), and that by using ziziphus leaf extract and nigella seed extract as an ointment.

Healthy twelve mature rabbits either sex, weighing 2-2.5 kg, bred locally were used.

Divided in to two groups (ziziphus group and nigella group) six rabbits of rabbits each one burned experimentally by using fire source directly on skin surface and then treated with local application of ointment (ziziphus leaf ointment and nigella sativa seed ointment) each one on it is group with daily dressing by using medical gauze.

This study appeared the benefit effect of ziziphus ointment and nigella ointment in burn healing in histopathological changes, but the group treated with ziziphus leaf extract (ointment) was better than the other group in cellular response to inflammatory process that occur during healing by early apparition of re-epithelialization.