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Monitoring immune responses in organ recipients by flow cytometry
Joint Authors
al-Mukhalafi, Zuha
Pyle, Robert
al-Husayn, Khalid
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 12, Issue 1 (28 Feb. 2001), pp.32-41, 10 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2001-02-28
Country of Publication
Saudi Arabia
No. of Pages
10
Main Subjects
Topics
Abstract EN
Allograft rejection remains a major barrier to successful organ transplantation.
Cellular and humoral immune responses play a critical role in mediating graft rejection.
During the last few years, monoclonal antibodies have been used as a new specific therapeutic approach in the prevention of allograft rejection.
Recently, the technology of flow cytometry has become a useful tool for monitoring immunological responses in transplant recipients.
The application of this valuable tool in clinical transplantation at the present time is aimed at, i) determining the extent of immunosuppressive therapy through T-cell receptor analysis of cellular components, ii) monitoring levels of alloreactive antibodies to identify high-risk recipients (sensitized patients) in the pre-operative period and iii) to predict rejection by monitoring their development postoperatively.
In future, further development of this technology may demonstrate greater benefit to the field of organ transplantation.
American Psychological Association (APA)
al-Mukhalafi, Zuha& Pyle, Robert& al-Husayn, Khalid. 2001. Monitoring immune responses in organ recipients by flow cytometry. Saudi Journal of Kidney Diseases and Transplantation،Vol. 12, no. 1, pp.32-41.
https://search.emarefa.net/detail/BIM-60628
Modern Language Association (MLA)
al-Mukhalafi, Zuha…[et al.]. Monitoring immune responses in organ recipients by flow cytometry. Saudi Journal of Kidney Diseases and Transplantation Vol. 12, no. 1 (Feb. 2001), pp.32-41.
https://search.emarefa.net/detail/BIM-60628
American Medical Association (AMA)
al-Mukhalafi, Zuha& Pyle, Robert& al-Husayn, Khalid. Monitoring immune responses in organ recipients by flow cytometry. Saudi Journal of Kidney Diseases and Transplantation. 2001. Vol. 12, no. 1, pp.32-41.
https://search.emarefa.net/detail/BIM-60628
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 38-41
Record ID
BIM-60628