Localised skin hyperpigmentation as a presenting symptom of vitamin B12 deficiency complicating chronic atrophic gastritis
Other Title(s)
تغيير موضعي لصبغة الجلد إلى اللون الداكن نتيجة لنقص فيتامين ب 12 بسبب التهاب مزمن بالمعدة
Joint Authors
al-Muammariyah, Muna
Samir, Nafisah
al-Waili, Ahmad
al-Shafii, Kawthar
Lakhtakia, Ritu
al-Shafii, Muhammad
Davidson, R.
Source
Sultan Qaboos University Medical Journal
Issue
Vol. 15, Issue 3 (31 Aug. 2015), pp.420-423, 4 p.
Publisher
Sultan Qaboos University College of Medicine and Health Sciences
Publication Date
2015-08-31
Country of Publication
Oman
No. of Pages
4
Main Subjects
Topics
Abstract EN
Vitamin B12 deficiency is common in developing countries and should be suspected in patients with unexplained anaemia or neurological symptoms.
Dermatological manifestations associated with this deficiency include skin hyper- or hypopigmentation, angular stomatitis and hair changes.
We report a case of a 28-year-old man who presented to the Sultan Qaboos University Hospital in Muscat, Oman, in November 2013 with localised hyperpigmentation of the palmar and dorsal aspects of both hands of two months’ duration.
Other symptoms included numbness of the hands, anorexia, weight loss, dizziness, fatigability and a sore mouth and tongue.
There was no evidence of hypocortisolaemia and a literature search revealed a possible B12 deficiency.
The patient had low serum B12 levels and megaloblastic anaemia.
An intrinsic factor antibody test was negative.
A gastric biopsy revealed chronic gastritis.
After B12 supplementation, the patient’s symptoms resolved.
Family physicians should familiarise themselves with atypical presentations of B12 deficiency.
Many symptoms of this deficiency are reversible if detected and treated early.
American Psychological Association (APA)
al-Shafii, Kawthar& Samir, Nafisah& Lakhtakia, Ritu& Davidson, R.& al-Waili, Ahmad& al-Muammariyah, Muna…[et al.]. 2015. Localised skin hyperpigmentation as a presenting symptom of vitamin B12 deficiency complicating chronic atrophic gastritis. Sultan Qaboos University Medical Journal،Vol. 15, no. 3, pp.420-423.
https://search.emarefa.net/detail/BIM-606558
Modern Language Association (MLA)
al-Shafii, Kawthar…[et al.]. Localised skin hyperpigmentation as a presenting symptom of vitamin B12 deficiency complicating chronic atrophic gastritis. Sultan Qaboos University Medical Journal Vol. 15, no. 3 (Aug. 2015), pp.420-423.
https://search.emarefa.net/detail/BIM-606558
American Medical Association (AMA)
al-Shafii, Kawthar& Samir, Nafisah& Lakhtakia, Ritu& Davidson, R.& al-Waili, Ahmad& al-Muammariyah, Muna…[et al.]. Localised skin hyperpigmentation as a presenting symptom of vitamin B12 deficiency complicating chronic atrophic gastritis. Sultan Qaboos University Medical Journal. 2015. Vol. 15, no. 3, pp.420-423.
https://search.emarefa.net/detail/BIM-606558
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 423
Record ID
BIM-606558