An overview on hepatitis C virus genotypes and its control
Joint Authors
Nuruz, Faysal
Shahin, Sidrah
Mujtaba, Ghulam
Nurin, Shumaylah
Source
The Egyptian Journal of Medical Human Genetics
Issue
Vol. 16, Issue 4 (31 Oct. 2015), pp.291-298, 8 p.
Publisher
Egyptian Society of Human Genetics
Publication Date
2015-10-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Topics
Abstract EN
Hepatitis C virus (HCV) is a blood borne, circular and positive single stranded virus with high spread rates.
With the passage of time the frequency of HCV is increasing in different parts of the world.
HCV is a major cause, which may end in liver cirrhosis and hepatocellular carcinoma.
HCV has six main genotypes with many subtypes, which have variable sequence homology with each other.
Symptoms can appear anytime from 2 weeks to 6 months, which include jaundice, fatigue, gray-colored stool, joint pain, belly pain, weakness, anorexia, itchy skin and dark urine.
Genotyping is more significant for planning of HCV treatment period and helps to cure HCV infections.
For the quantification and identification of hepatitis C virus-ribonucleic acid, many molecular techniques are performed; the most significant are HCV ELISA, quantitative HCV-RNA PCR and recombinant immunoblot assay.
PCR is the major technique targeting 50 untranslated region (UTR).
HCV can be transmitted by contaminated blood, ear and nose piercing and contaminated medical instruments.
To overcome the rate of HCV, guidance should be provided to make aware the persons about risk factors, transmission and prevention.
Discovery and designing of new therapies and vaccines to overcome this disease are the necessity of the present era.
Four types of vaccines such as vector vaccines, peptide vaccines, DNA vaccines and recombinant protein vaccines are available in clinical trials
American Psychological Association (APA)
Nuruz, Faysal& Shahin, Sidrah& Mujtaba, Ghulam& Nurin, Shumaylah. 2015. An overview on hepatitis C virus genotypes and its control. The Egyptian Journal of Medical Human Genetics،Vol. 16, no. 4, pp.291-298.
https://search.emarefa.net/detail/BIM-607940
Modern Language Association (MLA)
Nuruz, Faysal…[et al.]. An overview on hepatitis C virus genotypes and its control. The Egyptian Journal of Medical Human Genetics Vol. 16, no. 4 (2015), pp.291-298.
https://search.emarefa.net/detail/BIM-607940
American Medical Association (AMA)
Nuruz, Faysal& Shahin, Sidrah& Mujtaba, Ghulam& Nurin, Shumaylah. An overview on hepatitis C virus genotypes and its control. The Egyptian Journal of Medical Human Genetics. 2015. Vol. 16, no. 4, pp.291-298.
https://search.emarefa.net/detail/BIM-607940
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 296-298
Record ID
BIM-607940