Lipoprotein lipase gene variants : association with acute myocardial infarction and lipid profiles

Joint Authors

Bahrami, Mahyar
Barati, Hamzah
Jahani, Muhammad Mahdi
Fatimi, Ahmad
Sharifi, Zuhri
Iyad, Akram
al-Ipur, Sadiq
Golmohammadi, Taghi

Source

The Egyptian Journal of Medical Human Genetics

Issue

Vol. 16, Issue 4 (31 Oct. 2015), pp.327-332, 6 p.

Publisher

Egyptian Society of Human Genetics

Publication Date

2015-10-31

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Biology
Medicine

Topics

Abstract EN

Background : Studies showed that lipid metabolism disorders are significant risk factors for myocardial infarction and coronary artery disease (CAD).

Therefore, genes involved in lipid and lipoprotein metabolism pathways such as lipoprotein lipase (LPL), are proper candidates for susceptibility to CAD.

Aim : To investigate the possible association between LPL gene variants (HindIII (rs320) and PvuII (rs285)), acute myocardial infarction (AMI) and serum lipid levels.

Subjects and methods : The study population consisted of 211 patients with a diagnosis of premature AMI, and 203 age-matched individuals with normal coronary angiograms as controls.

Genotyping of HindIII and PvuII polymorphisms was done by the PCR-RFLP technique.

American Psychological Association (APA)

Bahrami, Mahyar& Barati, Hamzah& Jahani, Muhammad Mahdi& Fatimi, Ahmad& Sharifi, Zuhri& Iyad, Akram…[et al.]. 2015. Lipoprotein lipase gene variants : association with acute myocardial infarction and lipid profiles. The Egyptian Journal of Medical Human Genetics،Vol. 16, no. 4, pp.327-332.
https://search.emarefa.net/detail/BIM-608118

Modern Language Association (MLA)

Bahrami, Mahyar…[et al.]. Lipoprotein lipase gene variants : association with acute myocardial infarction and lipid profiles. The Egyptian Journal of Medical Human Genetics Vol. 16, no. 4 (2015), pp.327-332.
https://search.emarefa.net/detail/BIM-608118

American Medical Association (AMA)

Bahrami, Mahyar& Barati, Hamzah& Jahani, Muhammad Mahdi& Fatimi, Ahmad& Sharifi, Zuhri& Iyad, Akram…[et al.]. Lipoprotein lipase gene variants : association with acute myocardial infarction and lipid profiles. The Egyptian Journal of Medical Human Genetics. 2015. Vol. 16, no. 4, pp.327-332.
https://search.emarefa.net/detail/BIM-608118

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 331-332

Record ID

BIM-608118