Acute kidney injury : a rare cause
Joint Authors
Barki, Satish
Mishra, Mayank
Gupta, Devika
Gupta, Pooja
Mendonca, Satish
Kumar, R. S. Vasantha
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 26, Issue 5 (30 Sep. 2015), pp.980-982, 3 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2015-09-30
Country of Publication
Saudi Arabia
No. of Pages
3
Main Subjects
Topics
Abstract EN
We present a young lady who consumed hair dye, which contained paraphenylene diamine (PPD), as a means of deliberate self-harm.
This resulted in severe angio-neurotic edema for which she had to be ventilated, and thereafter developed rhabdomyolysis leading to acute kidney injury (AKI).
The unusual aspect was that the patient continued to have flaccid quadriparesis and inability to regain kidney function.
Renal biopsy performed 10 weeks after the dye consumption revealed severe acute tubular necrosis with myoglobin pigment casts.
This suggests that PPD has a long-term effect leading to ongoing myoglobinuria, causing flaccid paralysis to persist and preventing the recovery of AKI.
In such instances, timely treatment to prevent AKI in the form alkalinization of urine should be initiated promptly.
Secondly, because PPD is a nondialyzable toxin, and its long-term effect necessitates its speedy removal, hemoperfusion might be helpful and is worth considering
American Psychological Association (APA)
Mendonca, Satish& Barki, Satish& Mishra, Mayank& Kumar, R. S. Vasantha& Gupta, Devika& Gupta, Pooja. 2015. Acute kidney injury : a rare cause. Saudi Journal of Kidney Diseases and Transplantation،Vol. 26, no. 5, pp.980-982.
https://search.emarefa.net/detail/BIM-608811
Modern Language Association (MLA)
Mendonca, Satish…[et al.]. Acute kidney injury : a rare cause. Saudi Journal of Kidney Diseases and Transplantation Vol. 26, no. 5 (Sep. 2015), pp.980-982.
https://search.emarefa.net/detail/BIM-608811
American Medical Association (AMA)
Mendonca, Satish& Barki, Satish& Mishra, Mayank& Kumar, R. S. Vasantha& Gupta, Devika& Gupta, Pooja. Acute kidney injury : a rare cause. Saudi Journal of Kidney Diseases and Transplantation. 2015. Vol. 26, no. 5, pp.980-982.
https://search.emarefa.net/detail/BIM-608811
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 982
Record ID
BIM-608811