Fatty liver : a post-mortem study

Abstract EN

Background: There are many reports on fatty liver of the patients with abnormal liver function test of unknown cause but up to the knowledge of author, no post-mortem study is done on fatty liver Objective: The investigation was performed to observe fatty liver in patients who died of different medical causes Methods: In 570 patients, 354 males and 216 females who died during years 1991-2000 at internal medicine department, Taleghani hospital, Tehran, post-mortem evaluation was done.

After preparation of tissue, microscopic examination showed 47 cases of fatty liver.

Their medical history, physical findings and liver function tests were reviewed Results: of 47 cases, 19 [40%]were male and 28 [60%]were female.

Mild elevation of transaminase was seen in 24%, moderate increase in 18% and marked elevation in 13% Conclusion: prevalence of fatty liver in the patients who died was 10%, 55% of whom had abnormal liver function test.

One should think of hepatic steatonecrosis and consider the dosage of medicines with hepatic metabolism is such end stage eases