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Serum cystatin C as a predictor of acute kidney transplant rejection
Joint Authors
Shamkhi, Fadil B.
al-Yasin, Hedef D.
Ali, Ala A. Sh.
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 57, Issue 3 (30 Sep. 2015), pp.188-192, 5 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2015-09-30
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background: Accurate and rapid assessment of allograft function is essential.
Cystatin C has recently been proposed as an alternative marker of glomerular filtration rate (GFR).
Its diagnostic value for the longitudinal assessment of graft function has not been addressed well.
Objective: To study the validity of cystatin C as an early marker and predictor of acute transplant rejection in the first week post transplantation.
Subjects and Methods: Sixty six renal transplants recipients recruited.
The study conducted in four renal transplantation centers in Baghdad for the period from September to December 2011.
Serum creatinine and cystatin C concentrations measured 48 hours before transplantation and day 3 and 7 post transplantation.
Results: Serum Cystatin C observed to significantly increased at day 3 (p<0.0001) and still increased at day 7 in the rejection.
On day 3 areas under the receiver operating characteristic (ROC) curves were 0.749 for creatinine and 0.909 for cystatin C.
In patients with acute rejection, serum cystatin C level elevated earlier than serum creatinine.
Conclusion: Serum cystatin C seems to be a valuable marker of renal function in the first week post transplantation.
American Psychological Association (APA)
Shamkhi, Fadil B.& Ali, Ala A. Sh.& al-Yasin, Hedef D.. 2015. Serum cystatin C as a predictor of acute kidney transplant rejection. Journal of the Faculty of Medicine Baghdad،Vol. 57, no. 3, pp.188-192.
https://search.emarefa.net/detail/BIM-616850
Modern Language Association (MLA)
Ali, Ala A. Sh.…[et al.]. Serum cystatin C as a predictor of acute kidney transplant rejection. Journal of the Faculty of Medicine Baghdad Vol. 57, no. 3 (2015), pp.188-192.
https://search.emarefa.net/detail/BIM-616850
American Medical Association (AMA)
Shamkhi, Fadil B.& Ali, Ala A. Sh.& al-Yasin, Hedef D.. Serum cystatin C as a predictor of acute kidney transplant rejection. Journal of the Faculty of Medicine Baghdad. 2015. Vol. 57, no. 3, pp.188-192.
https://search.emarefa.net/detail/BIM-616850
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 191-192
Record ID
BIM-616850