Antinociceptive effects of the aerial parts of perovskia abrotanoides extracts in mice

Abstract EN

Anitinociceptive effect of the aqueous decoction and ethanolic maceration extracts of Perovskia abrotanoides aerial parte were studied using hot-plate and writhing tests.

The intraperitoneal injection of aqueous and ethanolic extracts of P.

abrotanoides practically showed no antinociceptive activity in hot-plate test.

In writhing test, both extracts exerted significant antinociceptive activity that was not inhibited by naloxone.

This showed that the extracts of P.abrotanoides had peripheral antinociceptive activities which not mediated by opioid receptors.