Multilayer amniotic membrane transplantaion for treatment of perforated corneal ulcerations
Other Title(s)
استخدام عدة طبقات من الغشاء الأمنيوسي في علاج قرحة القرنية المثقوبة
Joint Authors
Sad, Muhammad Sayyid
Masud, Ali Ahmad
Sad al-Din, Walid
Nobby, Jamal
Source
Issue
Vol. 33, Issue 2 (31 May. 2009), pp.87-94, 8 p.
Publisher
Assiut University Faculty of Medicine
Publication Date
2009-05-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Topics
Abstract AR
أجريت هذه الدراسة على 18 مريضا من قسم طب و جراحة العيون بطب أسيوط يعانون قرحة القرنية المثقوبة كان منهم 11 مريضا و 7 مريضات و كانت أعمارهم تتراوح بين 62 و 67 عاما و قد أجريت لهم عمليات ترقيع القرنية باستخدام عدة طبقات من الغشاء الامنيوسى و قد أوضحت هذه الدراسة نجاح هذه العملية في إحدى عشر مريضا (72.2 %) بدون مضاعفات و قد تم متابعة هذه الحالات حوالي 13 شهرا و لذلك ننصح بإجراء عملية ترقيع القرنية بالغشاء الامنيوسى في الحالات التي تعاني من قرح القرنية المثقوبة خاصة في ظل عدم توافر بنوك العيون في مصر.
Abstract EN
Aim : to examine the efficacy of amniotic membrane transplantation (AMT) in the treatment of perforated corneal ulcerations.
Methods : Eighteen patients (18 eyes) with perforated corneal ulcers were treated with multilayered AMT.
Separate amniotic membranes (AM) were transplanted as material to fill the stromal layer (AM filling), as a basement membrane (AM graft), and as a wound cover (AM patch).
The underlying causes of corneal perforation included herpes simples keratitis (6 eyes), mixed bacterial and fungal keratitis (4 eyes), bacterial keratitis (3 eyes), bullous keratopathy (3 eyes), and Moore's ulcer (2 eyes) Results : during the follow up period of 16.7 ± 7.2 months (8–21 months) after AMT, 13 (72.2 %) of 18 eyes healed with a mean 27.2 ± 9 epithelialization period of 18.3 ± 6 days (range 11 to 32 days).
The remaining 5 eyes (27.8 %) received second AMT, but disintegration of the amniotic membrane (AM) occurred and they received conjunctiva flap.
No patient developed major postoperative complications or graft rejection.
Conclusion : Multilayer amniotic membrane transplantation can be used as an emergency treatment for perforated corneal ulcerations to restore corneal integrity so that emergency penetrating keratoplasty (PK) can be avoided.
American Psychological Association (APA)
Sad al-Din, Walid& Sad, Muhammad Sayyid& Masud, Ali Ahmad& Nobby, Jamal. 2009. Multilayer amniotic membrane transplantaion for treatment of perforated corneal ulcerations. Assiut Medical Journal،Vol. 33, no. 2, pp.87-94.
https://search.emarefa.net/detail/BIM-61814
Modern Language Association (MLA)
Sad al-Din, Walid…[et al.]. Multilayer amniotic membrane transplantaion for treatment of perforated corneal ulcerations. Assiut Medical Journal Vol. 33, no. 2 (May. 2009), pp.87-94.
https://search.emarefa.net/detail/BIM-61814
American Medical Association (AMA)
Sad al-Din, Walid& Sad, Muhammad Sayyid& Masud, Ali Ahmad& Nobby, Jamal. Multilayer amniotic membrane transplantaion for treatment of perforated corneal ulcerations. Assiut Medical Journal. 2009. Vol. 33, no. 2, pp.87-94.
https://search.emarefa.net/detail/BIM-61814
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 93-94
Record ID
BIM-61814