Elimination of resistance of some isolates of Staphylococcus aureus to certain antibiotics by chloroform and acetone extracts of the plant Olivera dicumbens
Author
Source
al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah
Issue
Vol. 22, Issue 1 (31 Mar. 2009), pp.54-60, 7 p.
Publisher
University of Mosul College of Education for Pure Science
Publication Date
2009-03-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
Abstract AR
من مجموع 50 نموذجا تم الحصول عليها من الإنسان و من بيئات مختلفة، شخصت 18 عزلة منيا على أنها تعود لبكتريا Staphylococcus aureus .
اختبرت 6 عزلات من هذه البكتريا بهدف إزالة مقاومتها للمضادات الحيوية بواسطة مستخلصات الكلوروفورم و الاسيتون لنبات القزوح Olivera dicumbens .
عوملت عزلات البكتريا بالتراكيز التثبيطية تحت الدنيا نسبة قياس تم .Sub-Minimum Inhibitory Concentrations (Sub-MIC) المستعمرات التي فقدت مقاومتها للمضادات الحيوية.
وجد أن المستخلص الكلوروفورمي بتركيز 250 ملغم/ مل كان الأكثر فاعلية في إزالة مقاومة البكتريا للمضاد الحيويCiprofloxacin ، و وجد أن أعلى نسبة لفقدان المقاومة (38%) في العزلة الخامسة.
أما بالنسبة لفقدان المقاومة للمضاد الحيوي Ampicillin ، فقد ظهرت أعلى نسبة مقاومة (36 %) للمضاد الحيوي في العزلة السادسة.
من ناحية أخرى، ظهر اقل فقدان للمقاومة ضد المضاد الحيوي Nalidixic acid في العزلة الخامسة.
لم تلحظ تأثيرات واضحة للمستخلص الاسيتوني، عليه يمكن الاستنتاج بان المستخلص الكلوروفورمي ربما يكون قد عمل مطفرا، مزيال لمقاومة بعض عزالت Staph.
Aureus لبعض المضادات الحيوية.
Abstract EN
Out of 50 samples obtained from humans of different environments, 18 were diagnosed as Staphylococcus aureus.
6 out of these diagnosed isolates were tested for elimination of resistance to antibiotics by chloroform and acetone extracts of the plant Olivera dicumbens.
Bacterial isolates were treated with subminimum inhibitory concentrations (sub-MIC) of the above mentioned extracts.
Percentage of loss of resistance of colonies to antibiotics was measured.
Chloroform extract at the concentration 250 mg/ml was found to be the most effective concentration inducing resistance of this bacteria to the antibiotic Ciprofloxacin.
Highest percentage loss of resistance (38%) was found in the 5th isolate.
For loss of resistance to the antibiotic Ampicillin, highest resistance (36%) was found in the 6th isolate.
On the other hand, the least loss of resistance was found against the antibiotic Nalidixic acid in the 5th isolate.
No clear effect was obtained with the acetone extract.
It can, therefore, be concluded that the chloroform extract may have acted as mutagenic, eliminating the resistance of certain Staphylococcus aureus isolates to some antibiotics.
American Psychological Association (APA)
Mahmud, Abd al-Razzaq K.. 2009. Elimination of resistance of some isolates of Staphylococcus aureus to certain antibiotics by chloroform and acetone extracts of the plant Olivera dicumbens. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah،Vol. 22, no. 1, pp.54-60.
https://search.emarefa.net/detail/BIM-621211
Modern Language Association (MLA)
Mahmud, Abd al-Razzaq K.. Elimination of resistance of some isolates of Staphylococcus aureus to certain antibiotics by chloroform and acetone extracts of the plant Olivera dicumbens. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah Vol. 22, no. 1 (Mar. 2009), pp.54-60.
https://search.emarefa.net/detail/BIM-621211
American Medical Association (AMA)
Mahmud, Abd al-Razzaq K.. Elimination of resistance of some isolates of Staphylococcus aureus to certain antibiotics by chloroform and acetone extracts of the plant Olivera dicumbens. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah. 2009. Vol. 22, no. 1, pp.54-60.
https://search.emarefa.net/detail/BIM-621211
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 59-60
Record ID
BIM-621211