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Synthesis of 3-phenyl-4-styryl and 3-phenyl-4-hydroxy coumarins
Author
Source
al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah
Issue
Vol. 21, Issue 2 (30 Jun. 2008), pp.12-18, 7 p.
Publisher
University of Mosul College of Education for Pure Science
Publication Date
2008-06-30
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Abstract EN
In this paper the synthesis of substituted 3-phenyl-4-styryl and 3-phenyl-4-hydroxy coumarins is reported.
The substituted benzaldehydes were treated with 2-hydroxy acetophenone to give the corresponding chalcone, the hydroxy chalcone then reacted with phenyl acetic acid in pyridine and phosphorus oxychloride to give the intermediates esters, which then cyclized to 3-phenyl-4-styryl coumarins by their reaction with potassium hydroxide.
Substituted methyl salicylate were converted to the esters by their reaction with phenyl acetic acid and phosphorous oxychloride in pyridine, followed by cyclization with potassium hydroxide in pyridine to give 3-phenyl-4-hydroxy coumarins.
The structures of the synthesized compounds were established by physical and spectral methods.
American Psychological Association (APA)
Ismail, Shayma S.. 2008. Synthesis of 3-phenyl-4-styryl and 3-phenyl-4-hydroxy coumarins. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah،Vol. 21, no. 2, pp.12-18.
https://search.emarefa.net/detail/BIM-622442
Modern Language Association (MLA)
Ismail, Shayma S.. Synthesis of 3-phenyl-4-styryl and 3-phenyl-4-hydroxy coumarins. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah Vol. 21, no. 2 (Jun. 2008), pp.12-18.
https://search.emarefa.net/detail/BIM-622442
American Medical Association (AMA)
Ismail, Shayma S.. Synthesis of 3-phenyl-4-styryl and 3-phenyl-4-hydroxy coumarins. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah. 2008. Vol. 21, no. 2, pp.12-18.
https://search.emarefa.net/detail/BIM-622442
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 18
Record ID
BIM-622442